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Polymer Characterization Application Book
15 May 2014Download this application book from Waters to discover the latest methods in polymer characterization.
Download this application book from Waters to discover the latest methods in polymer characterization.
Developing differentiated polymers and deploying a sustainable operation are a key focus for the polymer and plastics industries. Current GPC/SEC methods are limited by a lack of resolution, separation times, and the volume of solvent consumed per analysis. The ACQUITY Advanced Polymer Chromatography (APC™) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization and a superior solution for achieving corporate innovation and sustainability goals. Key Features: New Column Technology – ACQUITY APC™ Columns utilize small, high pore volume bridged-ethyl hybrid particles that provide significant gains in stability, flexibility and faster separations. Stable Refractive Index Detection – The ACQUITY Refractive Index (RI) Detector is optimized for low dispersion, but with the low noise and drift performance required for accurate integration, even at low polymer concentrations. Precise Solvent Management - Precise flow delivery of the isocratic solvent manager ensures calibrated system provides accurate molecular weight data, day after day. Advanced Column Heating Module - Ensures highly repeatable thermal environment for banks of ACQUITY APC Columns. Empower® 3 Software with GPC option – Quickly and easily review, compare, and report polymer analysis data. Key Benefits Polymer Characterization - Provides unparalleled polymer peak resolution, particularly for low molecular weight oligomers. Speed of Analysis - Obtain accurate and repeatable polymer molecular weight information up to 5 to 20 times faster than traditional GPC/SEC methods. Cost Reduction - Lower analysis cost by reducing solvent consumption and waste disposal volumes. System Flexibility - Run diverse polymer applications on a single system.
Developing differentiated polymers and deploying a sustainable operation are two of the utmost challenges facing the polymer and plastics industries. Current GPC/SEC methods are limited by a lack of resolution for novel and complex polymeric entities, the time required to achieve satisfactory separation, and the volume of solvent consumed per analysis. Waters® ACQUITY® Advanced Polymer Chromatography™ (APC™) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization, and a superior solution for achieving corporate innovation and sustainability goals.
The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.
Take Advantage of the Ultimate in Productivity with UPLC and MS Waters’ next-generation single quadrupole MS detector for Ultra Performance LC™, the ACQUITY™ SQD, is designed specifically with the chromatographer in mind. The SQ Detector offers a simple yet powerful solution for your multi-tasking, fast-paced laboratory environment – with robust and reliable performance, and walk-up operation for any expertise level.
Acquire, Analyze, Manage, and Share Mass Spectrometry Information MassLynx™ Software increases the speed at which you can convert your sample data into valuable knowledge. It provides you with the fundamental platform to acquire, analyze, manage, and share your mass spectrometry information. MassLynx intelligently controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. MassLynx Software may acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. MassLynx’s Sample List is the core of the system. It maintains and consolidates the data on all of your samples. You also initiate any activities related to your sample from the Sample List. This "sample centric" approach simplifies the interaction with your LC/MS or GC/MS system, acquired data and processed results. Process Application-specific Data MassLynx Software features general purpose and specialized Application Managers that provide information for your specific MS analyses and data. Two come standard with MassLynx: QuanLynx™ for automated quantification included as standard with MassLynx OpenLynx™ for qualitative screening and identification Optional Application Managers can perform: Targeted quantitative analysis Mass-directed purification Metabolite identification Deconvolution of complex chromatograms Metabonomics & metabolomics Protein identification and protein characterization
Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) technology starts with unique 1.7 μm small-particle chemistries. Chromatographers no longer need to choose between speed and resolution–with UPLC you get both. Instrument Designed for Chemistry; Chemistry Designed for the Instrument The ACQUITY UPLC System has been holistically designed to match the performance needs of our innovative column chemistries with robust hardware, easy-to-use software and specialized support services. Small, pressure-tolerant particles High-pressure fluidic modules Minimized system volume Negligible carryover Reduced cycle times Fast response detectors Integrated system software and diagnostics With UPLC you have the ability to work more efficiently with higher speed, sensitivity and resolution at a much wider range of linear velocities, flow rates and backpressures to obtain superior results. The Waters ACQUITY UPLC System's high-pressure fluidics optimizes flow rates to make the most of small particle technology. The ACQUITY UPLC System's sample-handling design is designed to ensure exceptionally low carryover and reduced cycle time. And when interfaced with the Sample Organizer, it increases unattended sample capacity by ten times. High-speed detectors, both optical and mass, contribute to increased sensitivity and help manage the heightened speed and resolution requirements of UPLC. ACQUITY UPLC Systems are easily controlled, diagnosed, and monitored via a graphical system console interface. The console offers: Quick and easy access to critical instrument parameters Simple system start-up, elegant system status monitoring and predictive performance indicators to ensure maximum productivity Data management capabilities that are supported by both MassLynx™ and Empower™ software The ACQUITY UPLC System is also supported by Intelligent Device Management technology with our Connections® INSIGHT™ service, providing instrument diagnostics.
The ACQUITY UPLC® Evaporative Light Scattering (ELS) Detector is designed specifically for optimal UPLC®/ELS performance in a small footprint. When your analytes have poor to no UV/Vis response, or don’t ionize well by mass spectrometry, the ACQUITY UPLC ELS Detector with the ACQUITY UPLC System lets you analyze more molecules (including sugars, triglycerides, phospholipids, antibiotics, and natural products) in a single analytical run. Engineered for high volume or open access environments – anywhere large numbers of compounds are screened rapidly – the detector offers a convenient stackable design, easy maintenance, and long lamp lifetimes. Features of the ACQUITY UPLC ELS Detector: • Works with other detection techniques for a more comprehensive UPLC(/MS) analysis, for confidence that you’ve detected all of the components in your sample • Provides reproducible, reliable results with precise control over nebulization and desolvation processes for the measurement of temperature-sensitive molecules • Ensures the benefits of UPLC performance across the entire flow rate range with high data capture rates • One nebulizer for the entire flow rate range provides simplified set-up and the benefit of maximized performance. • Pre-aligned snap-in lamp is easy to change and provides maximum up-time. • Data rates up to 80 Hz provide improved peak definition and confidence in quantitative results. • Low gas pressure detection sends a signal to “stop flow” on your LC pump.
The SQ Detector 2 is compatible with the broadest range of chromatography platforms and ionization sources, the SQ Detector 2 is the ultimate single quadrupole mass detector for chromatography.IntelliStart™ guarantees maximum system performance and usability for reproducible results. A wide mass range enables uncompromised analysis of both low and high molecular weight species while versatile chromatographic options ensure compatibility with the broadest range of applications. Waters' Universal Ion Source Architecture offers easy compatibility with the widest range of analytes.
In 2004, Waters revolutionized liquid chromatography with the introduction of the ACQUITY UPLC System. At the heart of the system was Waters second generation hybrid, the Ethylene Bridged Hybrid (BEH) particle. In 2005, BEH Technology preparative particle sizes (2.5, 3.5, 5 and 10 μm) with the introduction of XBridge between HPLC and UPLC Technology platforms. BEH Technology particles offer: Excellent peak shape and efficiency for basic analytes A rational array of chromatographic selectivity Improvements in chemical stability at mobile phase extremes, particularly at elevated pH
The 2998 Photodiode Array (PDA) Detector offers advanced optical detection for Waters analytical HPLC, preparative HPLC, or LC/MS system solutions. Providing unprecedented trace impurity detection and quantitation, the 2998 PDA Detector’s integrated software and optics innovations deliver high chromatographic and spectral sensitivity. Enhanced software control provides flexibility for simultaneous 2D and 3D operation with either Empower™ or MassLynx™ Software. The Waters 2998 PDA Detector is designed for a range of laboratory applications, including trace impurity detection and quantification, compound identification and method development. Features of the Waters 2998 Photodiode Array PDA Detector: • Patented TaperSlit™ flow cell ensures high sensitivity while maintaining optimal spectral performance • Maximum signal-to-noise performance of <10 µAU • Simultaneous quantification of high- and low-level components within a single chromatographic separation for extended linear range • Flexible sampling rates for normal and fast LC separations from 1 to 80 Hz • Definitive compound identification & co-elution detection • Superior linear range with constant optical bandpass • Spectral exposure optimization to maximize the signal-to-noise across the entire wavelength range with a single Deuterium lamp • Thermal wander management for maximum baseline stability
