Application Note: Efficient neutralization of sanitized surfaces in aseptic manufacturing environments with ICR swabs
16 August 2019

In this application note, Merck Millipore illustrates that the ICR Swab broth medium provides efficient neutralization towards all tested disinfectants. For sanitizers with highly concentrated quaternary ammonium compounds, it is recommended that the sanitization workflow includes the minimization of sanitizer residues. Recommended procedures from the disinfectant manufacturer should be followed to ensure minimal risk of chemical residues on the surface, which should facilitate the neutralization process as well as ensure the safety of manufacturing drug products.