Application Note: Rapid, High Capacity Monitoring of T-Cell Activation for Adoptive Cell Therapy
11 February 2019

Monitoring the ex vivo activation of human T lymphocytes is key to developing an optimized and scalable adoptive cell therapy process. Described here is the development of a large-scale, multiplexed assay using high throughput flow cytometry to assess T-cell activation over time by combining immunophenotyping, cell proliferation, and cytokine profiling in a single assay.