Application of Ultraperformance Nanoscale Liquid Chromatography and High Resolution Accurate Mass Tandem Mass Spectrometry in ‘Omic Biomedical Studies of Infectious Disease and Cancer
16 Jul 2013
The molecular complexity inherent in biomedical studies places significant demands upon the analytical methodologies used to address the projects. Foremost, the instrumentation used to qualitatively and quantitatively characterize the biological samples must be highly reproducible across the cohort, across projects and across laboratories. Whilst individual 'omic analyses such as proteomics, lipidomics and metabolomics can independently provide much information, it has become increasingly clear that success in the understanding of the underlying molecular etiology of disease is best obtained via the acquisition and integration of datasets from all of these different ‘omic technologies. Thus, the analytical tools used must possess the flexibility to acquire data from these different classes of biomolecules. Finally, financial restrictions require that these datasets must be acquired in a high throughput manner. Waters
This webinar will discuss the application of ultraperformance nanoscale LC with high resolution accurate mass Q-Tof mass spectrometers to the acquisition of proteomic, metabolomic and lipidomic datasets in studies of infectious disease and cancer.