Structural mass spectrometry accelerates phenotyping

This presentation featuring Prof. John McLean, Associate Professor of Chemistry at Vanderbilt University, delves into the realm of accelerating phenotyping with structural mass spectrometry in drug discovery and synthetic biology. Originally showcased at the SelectScience^® Analytical Summit 2024, this presentation tackles the prevailing challenges in omics, such as isomers, and explores whether mass resolving power alone can address these hurdles. Prof. McLean examines ion mobility analyzers, exposomics, metabolomics, food omics, and strategies for enhancing molecular coverage. Key topics include isomer separation at high ion mobility resolving power and the utilization of artificial intelligence and machine learning in constructing a phenomics map.