New Automated Gel Electrophoresis Platform for DNA Size Selection
18 Apr 2011
Watch this interview with Sage Science to learn about the Pippin Prep, a new gel electrophoresis platform designed to automate size selection of DNA for next-generation sequencing applications. The instrument features a computer-controlled power supply and an integrated optical system, which enables user-defined size fractions to be collected automatically, avoiding time intensive manual gel pouring and gel cutting processes. Gel cassettes use an external DNA size standard run in a dedicated sample lane to determine the timing of size-selected collections. SelectScience.tv interview at AACR 2011.
About the company
Sage Science
Sage Science develops game-changing instrument products for sale to the Life Sciences research and Diagnostic laboratory markets. Our mission is to provide new systems to streamline and improve sample preparation workflows.
Sage Science is privately-funded. It is headquartered and manufactures at the Cummings Center in Beverly, MA, USA.
The Company released the Pippin Prep DNA size selection system in 2010. The Pippin has since established itself as the premium platform for high quality library construction for next gen sequencing applications.
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Pippin Prep DNA Size Selection System
Sage ScienceThe Pippin Prep is a preparative electrophoresis platform for collection of size-selected DNA samples. The system automates DNA size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries. The system collects fragments (depending on gel type) between 90 bp- 8kb. A higher quality of sample can be extracted, more reproducibly and with no cross-contamination, when compared to manual gel purification methods.
