Medium exchange with the Akura PLUS Hanging Drop System
1 Jul 2026
This video demonstrates the medium exchange workflow in the Akura™ PLUS Hanging Drop System, a platform designed for the generation and maintenance of uniform 3D spheroids. The process highlights careful liquid handling techniques to preserve drop stability and maintain spheroid integrity during culture.
Discover how the workflow supports consistent spheroid development and seamless transfer to Akura™ 96 microplates for downstream applications. This approach enables reliable long-term culture and integration into drug discovery and in vitro screening workflows.
About the company

InSphero
InSphero sets the standard for in vitro testing of novel drugs in the pharmaceutical and biotechnology industry with comprehensive solutions that provide greater confidence in decision making. Its robust and highly physiologically relevant suite of 3D InSight™ Microtissues and Services are used by major pharmaceutical companies worldwide to increase efficiency in drug discovery and safety testing. InSphero patent-pending technologies and methods enable large-scale, reproducible production of scaffold-free 3D microtissues driven solely by cellular self-assembly. The company specializes in delivering assay-ready and custom 3D models derived from liver, pancreas, and tumor tissues, to provide unrivalled biological insight into liver toxicology, metabolic diseases (e.g., diabetes and liver diseases), and oncology (with a focus on immuno-oncology). All InSphero microtissues are thoroughly validated to ensure the highest quality, certified for use in a variety of assays, and shipped globally to customers in a patented, easy-to-use spheroid-optimized platform, ready for research. Field application scientists and research staff with expertise in working with 3D models help ensure efficient integration and onsite training as needed. For customers who prefer an outsourcing strategy with fast turnaround, InSphero also offers contract research services utilizing their 3D microtissue models.




