Accelerating Science Feature
Tackling the PFAS measurement challenge with next-gen analytical standards
Accurate and reliable measurement of PFAS (per- and polyfluoroalkyl substances) at ultra-trace levels remains one of the most significant challenges facing analytical laboratories worldwide. As regulatory limits tighten and the list of regulated PFAS continues to expand, laboratories are under increasing pressure to deliver defensible, reproducible data across complex matrices.
As part of our wider Accelerating Science in PFAS feature, this topic explores how next-generation analytical standards are helping to address critical gaps in PFAS measurement, from improving quantitation and method validation to supporting interlaboratory harmonization and regulatory compliance. By examining advances in reference materials, isotopically labeled standards, and total fluorine approaches, we highlight how innovative solutions are enabling greater confidence in PFAS analysis and supporting robust decision-making in an evolving regulatory landscape.
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Guide to PFAS testing methods
For labs starting PFAS analysis or adding new compounds or matrices to their testing program, this summary of PFAS testing methods and guidelines from Restek can help you compare methods and select an appropriate workflow.
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PFAS reference material optimization to meet EPA regulatory compliance
Discover LGC Standards' work to investigate response factors to arrive at the optimum PFAS reference material design, and how this can be implemented to improve efficiency, free up resources, and give you confidence in your results.
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Chromatography revolutionizes PFAS analysis and detection
Explore how innovative chromatography techniques are enhancing detection and analysis, paving the way for safer environments and better public health.
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Tackling the challenge of forever chemicals with advanced mass spectrometry
Dr. Gauthier Eppe from the University of Liège discusses the importance of advanced analytical methods and the critical need for international discussion to improve regulation and understanding.
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PFAS analysis without compromise
Explore cost effective sample prep solutions from Agilent Technologies that meet the challenges of a regulated PFAS landscape for environmental PFAS analysis.
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Minimize PFAS background
Explore solutions to commonly faced challenges such as sample prep and background interference to improve sensitivity in PFAS analysis.
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The PFAS measurement crisis: A roundtable discussion
Live February 27, 2026
Register nowThis Accelerating Science Forum will bring together world-leading PFAS experts to discuss:
- Why current targeted PFAS methods capture only part of the total contamination picture, and the hidden risks this creates for laboratories, manufacturers, and regulators
- How next-generation analytical standards and non-targeted analysis (NTA) approaches can close critical PFAS data gaps and improve confidence in complex sample analysis
- The evolving global regulatory landscape, including EU REACH and U.S. EPA guidance, and what laboratories and organizations must do now to prepare
- The path toward international harmonization of PFAS measurement, reporting, and compliance frameworks
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