Using isotachophoresis as a novel method to improve the yield and quality of nucleic acid purification from FFPE samples

29 Apr 2021

To compare the performance of the Purigen Ionic system, DNA from 32 FFPE tissue blocks was purified with both the Ionic system and a commercially available column-based purification kit for FFPE samples. In this poster, Purigen assessed the quantity and quality of the purified DNA with the Qiagen MRef multicopy reference assay and the Agilent Technologies QC Plex Assay.

Ionic® Purification System

Purigen Biosystems

The Ionic® Purification System is a benchtop platform that provides automated extraction of DNA and RNA from biological samples. Using cutting-edge technology based on isotachophoresis, the Ionic system separates DNA and RNA freely in solution, without binding to or stripping nucleic acids from physical surfaces. The workflow is simple and efficient, while producing higher yields with higher purity, consistently and reliably.

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Using isotachophoresis as a novel method to improve the yield and quality of nucleic acid purification from FFPE samples