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The Samplicity® Filtration System Streamlines Chromatography Sample Preparation

20 Jun 2011

In this application note EMD Millipore compare sample filtration, prior to chromatographic separation, through hydrophilic polytetrafluoroethylene (PTFE) MillexR syringe filters with a 10 mL syringe to 0.45 µm hydrophilic PTFE Millex Samplicity® filters using the Samplicity filtration system. EMD Millipore’s Samplicity sample preparation system enables filtration of up to 8 samples directly into standard HPLC vials using vacuum driven filtration. The filtration speed for three different samples with varying composition and viscosity and cross-contamination of filtrates when processing multiple samples at one time are evaluated.

Samplicity® filtration system

Merck

Introducing a vacuum filtration system that makes sample preparation easy: the EMD Millipore Samplicity filtration system with Millex Samplicity membrane filters. With the Samplicity® filtration system and Millex Samplicity® membrane filters, EMD Millipore has transformed sample preparation forever. Advantages of the EMD Millipore Samplicity filtration system include:   •  Higher throughput with simultaneous vacuum filtration of up to eight samples   •  Ergonomic alternative to syringe filters   •  Easy sample preparation of even highly viscous or particulate-laden mixtures   •  Millex Samplicity membrane filters provide long-trusted quality with low extractables and low analyte binding   •  Choose the unit color to fit your lab—bold blue or glossy green Applications of the EMD Millipore Samplicity filtration system include sample preparation for:   •  Dissolution testing   •  High-pressure liquid chromatography (HPLC)   •  Ultra-high performance liquid chromatography (UHPLC or UPLC®)  •  Liquid chromatography – mass spectrometry (LCMS)

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The Samplicity® Filtration System Streamlines Chromatography Sample Preparation