Practical recommendations for cryo-EM single particle analysis reconstruction

22 Sept 2019

In this application note, Thermo Fisher Scientific details the main principles of image processing for single particle analysis (SPA) and details practical solutions to this rapidly evolving computational landscape. Multiple software packages have been suggested to combat the large data sets of electron microscopy images acquired and correlated during cryo-electron microscopy (cryo-EM) SPA.

Krios G4 Cryo-TEM for Life Sciences

Thermo Fisher Scientific

The Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) is a compact TEM. The instrument can be installed in labs with a ceiling height below 3.04 m (~10 ft), as the microscope height it below 3 meters. The Krios G4 Cryo-TEM has improved ergonomics for easier sample exchange. Data acquisition set up is easier and faster thanks to enhanced automation, systematic user guidance and advanced performance monitoring. Simultaneo

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