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PAT-enabled scaling and optimization of upstream bioprocesses

Thermo Fisher Scientific
15 Jan 2025

Scaling up a bioprocess is a complex, multi-variable challenge. Designing processes with scalable parameters is essential for ensuring confidence when transitioning from the research laboratory to clinical and production operations. Explore how modern bioreactors and process Raman technology can enhance bioprocess development and enable advanced process control strategies from pilot to production scale.

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Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer

Thermo Fisher Scientific

The Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer enables real-time, accurate spectral results for process monitoring. MarqMetrix All-In-One Process Raman Analyzer redesigns how Raman spectroscopy brings value to the Process Analytical Technology workflow by focusing on a user-centric experience through its rapid setup, portability, and ease of use for upstream and downstream R&D applications.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.BioreactorRaman

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PAT-enabled scaling and optimization of upstream bioprocesses