Multiomic 6-base data from cell-free DNA enhances the performance of liquid biopsy classifiers
14 Mar 2025Early cancer detection has the potential to significantly improve treatment outcomes and survival rates. Investigate the roles of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) as biomarkers for early-stage colorectal cancer (CRC) detection in cell-free DNA (cfDNA), using duet evoC for whole genome 6-base sequencing. Discover how the results support the hypothesis that distinguishing between 5mC and 5hmC can improve the sensitivity of liquid biopsy tests for early cancer detection.
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duet multiomics solution evoC
biomodalYour single solution for multiomics data - Uncover a true 6-base genome for unprecedented insights into current and future biological states. Access all four canonical bases and distinguish 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC) from a single 5ng DNA sample, in a single experiment, with high accuracy.