Mitochondrial toxicity in drug discovery

Mitochondria are critical regulators of normal cell function and health; consequently, their dysfunction plays a central role in many diseases. Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings, and market withdrawals, therefore it is important to identify mitochondrial toxicity during the early stages of the drug discovery process. Download this infographic to explore the impact of mitochondrial toxicity and learn of the benefits of novel in-vitro strategies for drug safety.