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Methotrexate analyzed with LC-MS

23 Mar 2022

The powerful anticancer drug, Methotrexate (4-Amino-N10- Methylpteroyl Glutamic Acid) acts as an antimetabolite and is used for the treatment of many neoplastic diseases including acute leukemia, osteosarcoma, non-Hodgkins lymphoma, and breast cancer.

Cogent Bidentate C18™ HPLC Columns

MicroSolv Technology Corp.

Cogent Bidentate C18™ HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and a straight chain C18 hydrocarbon bonded directly to the Silica Hydride surface with two separate points of attachment. The manufacturing of the Silica makes these columns virtually indestructible.

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Methotrexate analyzed with LC-MS