Measuring size, concentration, and zeta potential of LNPs with the DynaPro ZetaStar

Microfluidic formulation of RNA-containing lipid nanoparticles (LNP-RNA) is a common means of developing and producing this important non-viral modality of gene delivery. A key challenge during formulation is the selection of the specific lipids and formulation conditions to achieve the desired particle sizes and surface potential. Discover how by using the DynaPro™ ZetaStar™ instrument, researchers can rapidly characterize size, polydispersity, and zeta potential, comparing outcomes from two LNP formulation techniques to optimize efficiency and performance.