Interferences in ICP-MS: Do we still have to worry about them?

In this application note, PerkinElmer gives an overview with experimental data on interferences in ICP-MS. When the first commercial ICP mass spectrometer (ICP-MS) was introduced in 1983, it was of general opinion that this new technology freed analysts from worries about interferences. Now, many years later, we know that interferences do exist in ICP-MS, but we have a good understanding of them. Over the years, new techniques and technologies have been developed to reduce or eliminate them.

In routine ICP-MS analyses, two types of interferences exist: non-spectral (physical and matrix effects) and spectral (isobaric and polyatomic). Download this application note to look in more detail at both non-spectral and spectral interferences.