Incorporation of spatial mapping and confirmation of gene signatures into single cell RNA sequencing workflows

6 Feb 2020

The RNAscope technology is an advanced in situ hybridization assay that allows for the visualization of single-cell gene expression targeting RNA sequences directly in tissues. The proprietary double Z probe design in combination with the advanced signal amplification enables highly specific and sensitive detection of target RNAs in fresh frozen, fixed frozen, and formalin-fixed paraffin-embedded (FFPE) cells and tissues, with each dot representing a single RNA transcript.

RNAscope™ Technology

Advanced Cell Diagnostics

Independent of your genes of interest, thes easy RNA in situ hybridization assays use common reagents and protocols; providing universal assay conditions. All RNA-ISH kits contain reagents in a convenient ready-to-use (RTU) format, and chromogenic dyes are available to interrogate a single or two genes simultaneously. Most versatile are the RNAscope Multiplex Fluorescent Reagent Kits, enabling you to interrogate 1, 2 or 3 genes simultaneously.

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Incorporation of spatial mapping and confirmation of gene signatures into single cell RNA sequencing workflows