ResourceDrug Discovery & Development
Hypertension as a driver of cardiovascular and renal disease
1 Sept 2025This guide from Inotiv explores the pivotal role of hypertension in the progression of cardiovascular and renal diseases, emphasizing its impact on early drug development. It introduces three translational animal models used to study primary hypertension, kidney-driven hypertension, and metabolic dysfunction. Each model is evaluated for its physiological relevance, strengths, and limitations, with guidance on selecting the most appropriate platform for specific research goals. The resource also highlights Inotiv’s expertise in custom model development and preclinical research capabilities.