ResourceSeparations

HPLC-UV Analysis of Vitamin C from Tablets and Soft-Gels

9 Apr 2015

The verification of label claim data in nutraceutical formulations has come under scrutiny by the FDA. Manufacturers and contract testing labs alike are looking for accurate and scientifically valid methods that are suitable for use with different formulations. There were two primary goals of this project: firstly, to determine an accurate and reproducible means of analyzing Vitamin C and secondly, to demonstrate the suitability for analysis of two commercially available formulations of Vitamin C.

Gemini pH Flexible LC Columns

Phenomenex Inc

Setting the Standard for pH Method DevelopmentRugged reversed phase HPLC columns that offer extended lifetime under extreme pH conditions and excellent stability for reproducible, high efficiency separations. Take full advantage of high and low pH conditions (pH 1-12) to manipulate selectivity Expect longer column lifetime with patented TWIN-NX™ technology Ideal for analytical and preparative separations of basic and acidic compounds Who needs Phenomenex's Gemini HPLC columns? Method Developers: Extreme pH method flexibility Reproducible performance Purification Chemists: Purify bases at high pH Increased loading Increased retention Increased resolution Lab Managers: Extended column lifetime Consistent results.

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HPLC-UV Analysis of Vitamin C from Tablets and Soft-Gels