Generation of a High Throughput GABA Receptor Assay to Detect Benzodiazepines
30 Apr 2012This application poster identifies a high throughput GABAA α1β3γ2 and α2β2γ2 assay suitable for detecting benzodiazepines, which in functional assays would modulate the GABA response. The GABAA receptor is a ligand-gated ionotropic ion channel. Its endogenous ligand is GABA (y-aminobutyricacid), the major inhibitory neurotransmitter within the central nervous system.
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