From QC to quantitation: Utility of QReSS metabolites in FBS measurements

24 Nov 2025

Metabolomics is a rapidly growing field of research that has unique and proven advantages in systems biology and biomarker discovery. Great advances have been made over the past decade on the feasibility of mass spectrometry (MS)-based metabolomics. Despite the advancements, there remains a pervasive need for quality control (QC) as metabolomic experiments can experience unwanted variations that threaten the quality of the acquired data. The use of reliable QC measures is therefore critical to assess and prevent unwanted preanalytical and instrumental variation.

In this application note, the QReSS™ standard mixes (CIL cat no. MSK-QReSS1 and MSK-QReSS2) were used in the QC of metabolites from variably sourced FBS samples.

Resource details:

  • Resource type: Application note
  • Page count: 8
  • Read time: 6 mins

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.
From QC to quantitation: QReSS metabolites in FBS - SelectScience resources