Evaluating the Integration of CE, ESI and Mass Spectrometry for the Quantitative Analysis of Amino Acids in the Cationic Metabolome

Metabolomics can be defined as a comprehensive analytical approach for the study of all low-molecular-weight species present in a given biological system of interest. Development in recent years of an integrated interface technology composed of a capillary and emitter to form a seamless integrated process with electro-spray ionization, CESI, holds the promise of orders of magnitude in improvement of detections levels. This poster demonstrates the use of the CESI 8000 High Performance Separation - ESI Module from Sciex Separations for the quantitative analysis of amino acids in the cationic metabolome.