Drug metabolism in a gut-liver microphysiological system

23 Mar 2021

In this application note, CN Bio applies a multi-organ gut-liver MPS to recapitulate the kinetics and metabolism of the anti-inflammatory compound diclofenac.

Download the full protocol below to explore how this model can enable the accurate characterization of drug pharmacokinetics and be used to better predict appropriate drug dosing regimens.

Multi-chip Dual-organ (MPS-TL6) Plates by CN Bio

CN Bio

Multi-chip Dual-organ (MPS-TL6) consumable plates from CN Bio are used to culture interconnected 3D in vitro multi-organ-on-chip models under perfusion, such as Gut/Liver, or Lung/Liver, to generate clinically translatable data.

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Drug metabolism in a gut-liver microphysiological system