Does syringe filtration impact recovery of cannabinoids prior to potency testing

The objective of this study was to determine if using syringe filters (Sartorius Minisart^® RC, SRP, NY and NY Plus, all 0.2µm) either released interfering compounds or retained cannabinoids during sample preparation for HPLC testing. A blank matrix specimen of homogenized nettle leaf (Urtica dioica) was used for calibration and control and analyzed without cannabinoid for leachables. In addition, a true cannabis specimen was filtered using each of the four different filter types and analyzed for recovery of cannabinoids by HPLC.