Differentiation of M1- or M2- Macrophages from PBMC/Monocytes

Macrophages are tissue-resident professional phagocytes and antigen-presenting cells (APC), which differentiate from circulating peripheral blood monocytes. They perform important active and regulatory functions in innate as well as adaptive immunity. The PromoCell Macrophage Generation Media were designed for the straightforward and efficient differentiation of highly pure M1- or M2-macrophages directly from PBMC as a starting material. Included in this application note is a protocol overview using PromoCell M1-/M2-Macrophage Generation Medium DXF.