Determination of Aconitine in Body Fluids by LC/MS/MS

The Waters Alliance 2695 Separations Module is a high performance liquid chromatographic system with a quaternary, low-pressure mixing pump and inline vacuum degassing. Flow rates from 50 uL/min to 5 mL/min can be generated for use with 2.1 mm ID columns and larger. The autosampler has a maximum capacity of 120 vials (12x32, 2-mL) with programmable temperature control from 4 to 40°C. A heated column compartment provides temperatures from 5 degrees above ambient to 65°C. The detector is a photodiode array (model 2996) with a wavelength range of 190-800 nm and sensitivity settings from 0.0001-2.0000 absorbance units. All components of the HPLC are controlled through Waters Empower software.

Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy. To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you industry-leading analytical detection limits, resolution and sample throughput for all of your quantitative applications: Bioanalysis, ADME screening, food safety, environmental monitoring, clinical and more. Features: The best in accuracy and reproducibility of chromatographic peak area measurement Robust ZSpray™ atmospheric pressure ionization interface Versatile range of ionization options, including multi-mode ionization capability in a single run Optional QuanOptimize™ automated instrument optimization and quantitative method development tools TargetLynx™ dedicated application managers for your specialized analytical requirements  Small footprint that sits easily on your laboratory benchtop