ResourceSeparations
Comprehensive high-resolution targeted LC-MS/MS analysis of challenging signalling lipids
10 Sept 2024LC-MS has been the standard choice for the analysis of signalling lipids, but the method poses specific challenges, such as peak tailing and loss of recovery for phosphate groups containing lipids. Explore an optimized LC-MS/MS method from YMC Europe that covers 388 signalling lipids from 17 lipid classes. Discover how the bioinert coated YMC Accura Triart C18 column combines high resolution with high sensitivity for phosphate groups containing lipids.
Related products
Request Quote for All Products
(Bio)inert RP/HILIC (U)HPLC Columns: YMC Accura Triart
YMC EuropeBioinert YMC Accura Triart RP and HILIC columns are available for the analysis of critical substances including selected proteins, (oligo)nucleotides and metal-coordinating compounds such as organophosphates.
Links
Tags
LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Compound AnalysisCompound analysis is used to discover specific compounds that could be promising candidates for pharmaceutical use. This potential is identified when compounds have the desired effect, such as interaction with a target protein, during high throughput screening.LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Chromatography ColumnTandem MS