Charge variant analysis
27 Jun 2021In this application compendium, Agilent Technologies presents a ‘how-to’ guide for ion-exchange chromatography for biomolecule analysis. It includes application notes demonstrating how to refine your charge variant analysis of monoclonal antibodies and how analysis times can be significantly reduced, increasing throughput without compromising analytical performance.
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Agilent 1260 Infinity II Bio-Inert LC System
Agilent TechnologiesThe 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.
Agilent Bio MAb
Agilent TechnologiesThorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies.
Agilent Bio IEX
Agilent TechnologiesAgilent Bio Ion-Exchange HPLC columns are packed with polymeric, nonporous, ion-exchange particles. Bio Ion-Exchange Columns are designed for high resolution, high recovery and highly efficient separations of peptides, oligonucleotides and proteins.