BrightSite™ Near-Infrared Fluorescent Targeting Agents for Optical Imaging of Disease

25 Mar 2011

This application note by LI-COR Biosciences assesses the use of NIR dyes for clinical in vivo imaging. In the NIR wavelength range (700–900 nm) tissue autofluorescence is lower and light can penetrate more deeply than in visible light wavelengths. Here NIR fluorophores are used to image mice tumours and bone structure.

IRDye 800CW Infrared Dyes

LICORbio

Imaging probes conjugated to IRDye 800CW and IRDye 700DX have propelled more than 20 Phase I and Phase II clinical trials worldwide.

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IRDye 680LT Infrared Dyes

LICORbio

IRDye 680LT dye is highly soluble in water and is significantly brighter and more photostable than many other 700 nm near-infrared dyes.

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