Analysis of Drugs: Single Fast Approach for the Determination of Most Common Drugs and Their Metabolites Using GC-TOFMS

The aim of the work in this application note was to develop a complete analytical method using a fast Gas Chromatograph coupled with a Mass Spectrometer with Time Of Flight technology (TOF MS). This system allowed a unique fast analysis (less than 8 minutes) of the most common and used drugs (Cannabis, opioids, opiates and Cocaine), their metabolites and their adulterants from biological and autopsy samples with excellent linearity, sensibility and repeatability.