Advancing drug discovery through function-focused single-cell profiling

This whitepaper explores how function-focused single-cell profiling can enhance drug discovery by enabling direct measurement of cellular behaviour rather than relying on inferred genomic or transcriptomic data. It highlights the limitations of traditional single-cell approaches, including variability from droplet encapsulation, Poisson-driven distribution inefficiencies, and the inability to capture dynamic cellular functions.

Discover how the Lightcast platform addresses these challenges by combining droplet microfluidics, optical electrowetting-on-dielectric (oEWOD), and machine learning to enable real-time, high-throughput functional analysis at the single-cell level. This integrated approach allows precise droplet control, improved cell viability, and efficient sequential assays, supporting faster identification of functional drug candidates while reducing cost and complexity in early-stage development.

Resource details:

• Resource type: Whitepaper
• Page count: 5
• Read time: 8 mins