Real-time FT-IR monitoring of reaction kinetics for drug design

Reversible covalent binding is emerging as a promising strategy in drug design, offering greater control over drug-target interactions while helping to reduce the risks associated with irreversible binding. Understanding how these reactions progress, reach equilibrium, and respond over time is critical for optimizing compound design and advancing safer therapeutics.

In this resource, discover how the ABB MB-Rx In Situ Reaction Monitor can simplify the study of reversible covalent binding reactions through real-time Fourier transform infrared (FT-IR) monitoring. By providing continuous insight into reaction kinetics and equilibrium without manual sampling, the system helps researchers optimize compounds more efficiently and make faster, data-driven decisions. The result is a streamlined workflow that supports the development of safer, more effective drug candidates.

Resource details:

Resource type: Application note
Page count: 2
Read time: 3 mins