A quick and robust mass spectrometry-based method for the detection of SARS-CoV-2
10 Nov 2023In this application note, Thermo Fisher Scientific presents a reliable mass spectrometry-based method for detecting SARS-CoV-2 peptides, crucial biomarkers for active COVID-19 infection. The study demonstrates the detection of six peptides from recombinant protein samples spiked onto nasopharyngeal swabs or saliva, placed in viral transport media, and enzymatically digested. The results show sub/low-femtomole on-column detection and quantification limits for each peptide, showcasing the potential of utilizing the TSQ Altis™ MD mass spectrometer for COVID-19 testing.
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TSQ Altis™ MD Mass Spectrometer
Thermo Fisher ScientificDevelop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories.