ResourceSeparations

A New Approach to Authentication and Routine Screening of Ginsenoside Isomers in Functional Food Products

A New Approach to Authentication and Routine Screening of Ginsenoside Isomers in Functional Food Products

30 Jun 2016

Ginseng is a slow-growing perennial plant believe to offer different therapeutic benefits such as CNS stimulant activity, hypoglycemic properties and sedative effects. Ion mobility is a rapid orthogonal gas separation phase technique that allows another dimension of separation to be obtained within an LC timeframe. This application note investigates the use of IM separation in combination with microflow chromatography to provide a route to specific and unambiguous identification of ginsenosides.

ACQUITY UPLC M-Class System

Waters

The analysis you’ve always desired for nano- to microscale separations The ACQUITY UPLC M-Class System delivers the most robust, reliable, and highest quality nano- to microscale UPLC separations to every laboratory performing LC/MS analyses. With unprecedented usability, the ACQUITY UPLC M-Class System enables laboratories to succeed in analyzing compounds that are severely limited in amount or availability, even amid a complex matrix over several orders of magnitude. Confidently achieve your laboratory goals with high-efficiency ACQUITY UPLC M-Class Columns ranging from 75 µm to 1 mm I.D. by using complementary mass spectrometry to support our full range of column I.D.’s, or run 300 µm to 1 mm I.D. columns with optical detection.The system also offers a range of flexible configurations for HDX technology, UV detection, and 2D analysis.ACQUITY UPLC M-Class System Features: Highest sensitivity - UPLC separations yield increased analyte concentration for higher UV and MS signal responses Maximum chromatographic resolution - New 15k psi-capable ACQUITY UPLC M-Class Columns deliver sub-2-µm particle performance Faster nano- and microscale separations - Increased operating pressures yield maximum flexibility for higher throughput analyses Higher resolution with longer columns - Increased pressure enables more separation power Confidence in sample analysis - New non-reactive wetted surfaces throughout the fluidic path minimize absorptive losses Increased solvent compataibility - Improved range of solvent blends precisely metered for gradient fidelity Increased sample capacity - Sample organizer compatibility allows you to store a wide variety of plates and vials in the system for longer, unattended operation UV compatibility - UV flow cells compatible with 300 µm to 1.0 mm I.D. columns to augment your UPLC/MS analysis Scalability - With flow rates from 200 nl/min to 100 µL/min, achieve the best chromatographic performance, from 75 µm to 1.0 mm I.D. columns covering a 170-fold range of column sizes Increased flexiblity - More value configurations enable a variety of applications, icnreased throughput, and maximized peak capacity

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Natural Products Application Solution with UNIFI

Waters

The Waters Natural Products Application Solution with UNIFI provides a bottleneck breakthrough solution for analyzing natural products. Built around the UNIFI Scientific Information System, it converts traditionally labor intensive and cumbersome multistep sample profiling procedures into a workflow-driven and significantly streamlined process. It incorporates a unique Traditional Medicine Library into the workflow, along with automatic fragment ion confirmation implementation. As a result, the process of ingredient profiling can move from data acquisition to review of a completed analysis with the click of a button. The solution also provides users with test samples, user-required analytical method templates, and comprehensive workflow templates. All is managed into an easy-to-use solution that minimizes technical requirements for analysts.

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Screening Platform Solution with UNIFI

Waters

The only comprehensive screening solution The Waters® Screening Platform Solution with UNIFI™ is the first and only comprehensive screening solution – target, identify, quantify, and review using a streamlined analytical workflow that enables more accurate results across a wide range of applications.The platform is holistically designed, combining world-class instruments, software, Waters’ Analytical Standards and Reagents, and chemistries. All backed by Waters expert Service and Support.Based on the UNIFI Scientific Information System, the Platform Screening Solution facilitates data standardization so that information can be exchanged and transferred among departments and third-party partners. It enables all laboratory functions to work with a common backbone of analytical information including methods, processed results, and historical data and reports.Screening Platform Solution Includes: ACQUITY UPLC® I-Class System- Increased resolution and reduced peak widths result in unrivalled sensitivity.- Maximizes peak capacity to enhance MS sensitivity.- Provides the lowest carryover, complementing MS sensitivity and extending linear dynamic range.- Maximizes the benefits of sub 2-μm particle columns with the lowest dispersion. Xevo® G2-S QTof- Analyze the broadest range of compounds in the most complex samples. - StepWave™ ion optics allow for unsurpassed levels of robust sensitivity. - Delivers superior UPLC®-compatible mass resolution, matrix-tolerant dynamic range, quantitative performance, mass accuracy, and speed of analysis – simultaneously. UNIFI Scientific Information System- Consolidates state-of-the-art data acquisition, processing, and management capabilities to revolutionize screening processes. - Store, make use of, and share all data, methods, and reports. - UNIFI’s scientific library enables you to make use of your prior work, as well as the data and findings of colleagues. Analytical Standard and Reagents- Precisely formulated, ready-to-use, and will help analysts derive optimal performance from their LC and MS instruments.- Ensure quality and consistency from day-to-day, system-to-system, and lab-to-lab.

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