ResourceDrug Discovery & Development
3D aggregation of tumor spheroids in the Akura 384 spheroid microplate
3 Jul 2026This resource describes the generation of 3D tumor spheroids using the Akura™ 384 Spheroid Microplate, an automation-compatible platform designed for high-throughput in vitro applications. The protocol outlines key steps including plate preparation, cell seeding, and optimization of aggregation conditions to ensure reproducible spheroid formation.
The system enables uniform spheroid formation and supports downstream workflows such as high-content imaging and drug screening. With its scalable 384-well format and compatibility with automated liquid handling, the platform is suited to applications in oncology research, toxicology, and drug discovery.
Resource details:
- Resource type: Application note
- Page count: 4
- Read time: 8 mins
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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.3D Cell CultureCulturing cells in three dimensions allows more physiologically relevant observations to be made regarding cellular interactions and gene expression. 3D models provide a more accurate representation of cells in vivo and are more stable than 2D cultures, making them very useful for long-term studies.High Throughput ScreeningCancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
