UHPLC and HPLC Systems Products & Reviews

Experience the power of analytical compound isolation

The 1260 Infinity II LC System is a robust HPLC that offers the widest choice of modules for analytical HPLC and entry-level UHPLC, delivering the performance, reliability, and robustness you need for highest confidence in your daily results.

The 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.

The 1260 Infinity II GPC/SEC System is designed to meet the challenges faced by today’s polymer analysis. This versatile size exclusion chromatography (SEC) and gel permeation chromatography (GPC) system provides accuracy and high performance.

Increase resolution where you need it with the 1290 Infinity III 2D-LC System, which offers comprehensive two-dimensional liquid chromatography (2D-LC), (multiple) heart-cutting 2D-LC analysis, and high-resolution sampling. This system allows you to use 2D-HPLC for making buffer separations compatible to MS detection, while easy-to-use software enables fast method setup and refined data analysis.

The 1260 Infinity II Prime LC is a versatile HPLC offering the highest functionality and operational convenience for analytical HPLC and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min. This versatile HPLC system is a perfect front end for your MS system. 

The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.

An ideal solution for trace level PFAS analysis with LC/MS/MS

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) and conductivity detection, and automated sample injection, for the purification of proteins

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) detection, buffer blending options, for rapid pH scouting during the purification of proteins, peptides, and nucleic acids

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) detection, expanded scouting options, large-sample injection, and column switching of up to 5 columns, for method development

The D-100 System is the future of A1c testing and offers Smart HPLC results, variant detection*, and can aid in diabetes diagnosis without comprising speed and efficiency.

Experience New Benchmarks of Intelligence, Efficiency, and Design

The new, integrated i-Series LC system maintains the excellent performance of its predecessor while addressing the need for automation efficiency.

The LC-2030C NT provides a simple touch-screen user interface and a workflow that requires no specialist training.

The Nexera XS inert system offers an ideal solution for the separation of biomolecules by combining the elevated pressure tolerance of a UHPLC system with complete inertness of the sample flow path, ensured by the absence of wetted metal surfaces and offering ultra-high resistance to corrosion.

At-line cell culture media analysis. Results on 30+ components in under 10 minutes. When and where is your call. With the REBEL, now is always on the table.

The most powerful solution to the most critical need in separation science today.

The Waters Alliance 2695 Separations Module is a high performance liquid chromatographic system with a quaternary, low-pressure mixing pump and inline vacuum degassing. Flow rates from 50 uL/min to 5 mL/min can be generated for use with 2.1 mm ID columns and larger. The autosampler has a maximum capacity of 120 vials (12x32, 2-mL) with programmable temperature control from 4 to 40°C. A heated column compartment provides temper…

Making more informed decisions in less time is a universal asset in today's laboratory. Ultra Performance LC™ (UPLC™ ), a new category of separation science pioneered by Waters, will eliminate significant time and cost per sample from your analytical process—while improving the quality of your results. With UPLC technology you benefit from: more data, faster unparalleled sensitivity greater efficiency and confidence in…

The analysis you’ve always desired for nano- to microscale separations The ACQUITY UPLC M-Class System delivers the most robust, reliable, and highest quality nano- to microscale UPLC separations to every laboratory performing LC/MS analyses. With unprecedented usability, the ACQUITY UPLC M-Class System enables laboratories to succeed in analyzing compounds that are severely limited in amount or availability, even amid a comp…

The Alliance™ HPLC System is the flexible and reliable workhorse that meets your fundamental HPLC separation requirements.

Count on the Waters Arc™ HPLC System for high-efficiency separations and quality data to help meet your regulatory requirements with confidence.  The Arc HPLC system allows you to easily replicate and improve the performance of existing LC methods without compromising data quality.

Along with the reliability, ruggedness, high quality, and configuration flexibility you expect from the ACQUITY™ UPLC™ PLUS Series, the Waters™ ACQUITY Premier System delivers a step change in chromatographic performance, lab efficiency, and risk control.

The Breeze™ 2 HPLC System delivers technology and performance in an affordable, compact, and user-friendly system platform. Complete with software, pump, detector and injector, the system comes pre-configured for different levels of HPLC operational needs. From teaching purposes to daily analytical work, the Breeze 2 HPLC System integrates simplicity, sensitivity, accuracy, and reliability. It is ideal for any organization see…