Protein Purification > Protein Ion Exchange Products & Reviews

TOYOPEARL GigaCap® Series offers highest capacity for ion exchange purification steps

500 g, cation exchange resin, sodium form, 1% crosslinkage, 50–100 dry mesh size, 300–1,180 µm wet bead size, ~3,500 MW limit

TOYOPEARL NH2-750F offers a high binding capacity across a range of pH values and conductivities

TSKgel SuperQ-5PW is especially suited for industrial purification of oligonucleotides

PhyTip® columns are the gold standard for high-throughput, small-scale purification of proteins, antibodies, plasmids, and viral vectors. By integrating advanced chromatography directly into a pipette tip, PhyTip® columns eliminate manual bottlenecks and deliver high quality purification with true "walk-away" automation.

Agilent Bio Ion-Exchange HPLC columns are packed with polymeric, nonporous, ion-exchange particles. Bio Ion-Exchange Columns are designed for high resolution, high recovery and highly efficient separations of peptides, oligonucleotides and proteins.

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies.

PL-SAX for Biomolecules is ideal for the anion-exchange HPLC separations of proteins and deprotected synthetic oligonucleotides under denaturing conditions.

PL-SCX is a macroporous PS/DVB matrix with a very hydrophilic coating and strong cation-exchange functionality. 

ZORBAX Ion Exchange columns are available as both Strong Anion-Exchange (SAX) and Strong Cation-Exchange (300SCX) columns. 

PL-SAX strong anion-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

PL-SCX strong cation-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

When the highest resolution matters in ion exchange chromatography

The ready-to-use QuickPick DEAE weak anion exchange kit is intended for the fractionation of proteins based on weak ion exchange. It is optimized for use with the PickPen magnetic tool.

The ready-to-use QuickPick DEAE weak anion exchange kit is intended for the fractionation of proteins based on weak ion exchange. It is optimized for use with the PickPen magnetic tool.

The ready-to-use QuickPick CM weak cation exchange kit is intended for the fractionation of proteins based on weak ion exchange. It is optimized for use with the PickPen magnetic tool.

The ready-to-use QuickPick CM weak cation exchange kit is intended for the fractionation of proteins based on weak ion exchange. It is optimized for use with the PickPen magnetic tool.

TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins.

500 g, cation exchange resin, sodium form, 1% crosslinkage, 100–200 dry mesh size, 150–300 µm wet bead size, ~3,500 MW limit

500 g, cation exchange resin, sodium form, 1% crosslinkage, 200–400 dry mesh size, 75–150 µm wet bead size, ~3,500 MW limit

500 g, cation exchange resin, sodium form, macroreticular, 20–50 dry mesh size, 300–1,180 µm wet bead size, >1,000,000 MW limit

25 ml, hydrophobic cation exchange chromatography media, 70 µm particle size

Pkg of 1, 1 ml, column prepacked with Nuvia S Strong Cation Exchange Chromatography Media

Pkg of 1, 1 ml, column prepacked with Nuvia Q Strong Anion Exchange Chromatography Media

Pkg of 1, 1 ml, column prepacked with Nuvia cPrime Hydrophobic Cation Exchange Chromatography Media