iPSC Derived Cell Lines Products & Reviews

A highly defined, scalable, and consistent source of human central nervous system (CNS) neurons. ioGlutamatergic Neurons, part of the bit.bio ioCells portfolio, are reprogrammed from human induced pluripotent stem cells (iPSC) using bit.bio's precise reprogramming technology: opti-ox™ (optimised inducible overexpression).

Cellartis Human iPS Cell Line Kits

Human iPSC-derived microglia expressing Cas9 for rapid gene knockout generation

A highly defined, scalable, and consistent source of human central nervous system (CNS) neurons carrying the disease-relevant 50 CAG trinucleotide repeat expansion associated with Huntington’s disease.  ioGlutamatergic Neurons HTT 50CAG/WT have been reprogrammed from human-induced pluripotent stem cells (iPSCs) using bit.bio’s precise reprogramming technology: opti-ox™ (optimized inducible overexpression).

ioMicroglia are human induced pluripotent stem cell (iPSC)-derived microglia, precision reprogrammed using opti-ox™ technology. Within 10 days post-revival, ioMicroglia are ready for experimentation, expressing (>90%) key markers, including TMEM119, P2RY12, and IBA1. ioMicroglia display key functional traits including phagocytosis and proinflammatory cytokine secretion and can be co-cultured with ioGlutamatergic Neurons™.

iPSC drug discovery services from Ncardia

Taking products from concept to clinic

Proven, relevant iPSC-derived cell models from Ncardia

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

Build tomorrow’s cell therapies and cell-based disease models using TARGATT™ Human Induced Pluripotent Stem Cell (hiPSC) Kits. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions), TARGATT™ hiPSC technology enables expression of large proteins and multi-protein complexes in hiPSC-derived human cell lines.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a newborn male donor's cord blood.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a newborn female donor's cord blood.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a 74-year-old male donor's pulmonary fibroblasts.

axoCells Human iPSC-Derived Sensory Neurons (=0.5 million cells) for pain and sensation research. Sensory neurons made from iPSCs which were generated from a newborn male donor's cord blood.

axoCells Human iPSC-Derived Motor Neurons (=2 million cells) for neuroscience research. Motor neurons made from iPSCs generated from a 62-year-old asymptomatic ALS (C9ORF72 carrier) male donor's dermal fibroblasts.

axoCells Human iPSC-Derived Motor Neurons (=2 million cells) for neuroscience research. Motor neurons made from iPSCs generated from a 64-year-old symptomatic ALS (C9ORF72) female donor's dermal fibroblasts.

axoCells Human iPSC-Derived Motor Neurons (=2 million cells) for neuroscience research. Motor neurons made from iPSCs generated from a 74-year-old male donor's pulmonary fibroblasts.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from an 87-year-old Alzheimer's Disease (APOE4 HOM) female donor's dermal fibroblasts.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a 38-year-old Alzheimer's Disease (PSEN1 L286V) female donor's dermal fibroblasts.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a 53-year-old Alzheimer's Disease (PSEN1 M146L) male donor's dermal fibroblasts.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs which were generated from a 31-year-old Alzheimer's Disease (PSEN1 A246E) female donor's dermal fibroblasts.

axoCells Sensory Neuron Maintenance Media (250ml) and Sensory Neuron Maximizer Supplement (1 ml), optimized for maturation of sensory neurons for pain and sensation research. Suitable for use with axoCells Sensory Neurons (ax0055, ax0555).

axoCells Human iPSC-Derived Motor Neurons (=2 million cells), Motor Neuron Maintenance Media (200ml), Motor Neuron Accelerator Supplement (1 ml), GDNF (10 µg), BDNF (10 µg), CNTF (20 µg), optimized for maximum post-thaw recovery of motor neurons. Motor neurons made from iPSCs generated from a 74-year-old male donor's pulmonary fibroblasts.

axoCells Human iPSC-Derived Neural Stem Cells (=1.5 million cells) for maturation to cortical excitatory neurons or striatal neurons for neuroscience research. NSCs made from iPSCs generated from a 48-year-old Huntington's Disease (HTT CAG50) female donor's dermal fibroblasts.

axoCells Striatal Neuron Basal Media (2 x 250ml), Striatal Neuron Media Supplement (2 x 7.5ml) and Differentiation Supplement A (1 vial) optimized for maturation of striatal neurons (medium spiny neurons) for neuroscience research.