LC-MS Products & Reviews

Alfa Chemistry’s Deformulation and Reverse Engineering Services provide analysis of product composition, material structure, and formulation using qualitative and quantitative techniques. The service supports ingredient identification, formulation profiling, and structural analysis to aid product improvement, quality benchmarking, supply continuity, and technical comparison across diverse materials.

Alfa Chemistry’s Pharmaceutical Analytical Services offer expert testing and characterization throughout drug development and production. Using a cGMP-compliant laboratory and advanced analytical techniques, we provide biopharmaceutical characterization, impurity profiling, stability assessment, and formulation analysis to ensure product safety, efficacy, and regulatory compliance.

Syft Tracer Pharm11 redefines genotoxic impurities analysis for compliant pharma and CDMO workflows as fast and easy with no sample preparation. This solution includes next-gen SIFT-MS Syft Tracer, a CTC autosampler, a high-throughput (HTP) inlet, and 21 CFR Part 11 compliant software SyftAuditTracer.

Syft SafetySure is a class-leading solution for rapid, reliable detection of hazardous chemicals such as fumigants and volatile toxic industrial chemicals in workplace settings. It provides reproducible identification and quantification of hazardous chemicals commonly found in workplaces such as methyl bromide, sulfuryl fluoride, chloropicrin, ethylene dibromide, ethylene oxide and phosphine. It's simple to use with no consuma…

Resolve cross-functional pathways

Unraveling the complexity of disease

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

Transforming medicine with metabolomics

Decoding lipid-driven biology

Efficient workflows for busy laboratories

Metabolomics in nutrition, microbiome, and disease

SEQUEST Cluster is a complete, preconfigured proteomics solution that enables accelerated throughput of increasingly complex, multidimensional informatics.Product detail:The SEQUEST Cluster offers a scalable solution for computing the large volumes of data typical in most proteomics analyses using LC/MS. Protein database search times are dramatically reduced by harnessing the power of several processing units in one, increasin…

Enzymatic digestion of proteins in polyacrylamide gel slices and subsequent analysis of the peptides by mass spectrometry has become a routine procedure in protein analysis. In solution digestion protocols for bottom-up proteomics complement it. The DigestPro MSi automates all those procedures to achieve high throughput under controlled and reproducible conditions.

PHOTONIS Channeltron detectors provide the highest sensitivity due to superior signal collection and noise reduction, effectively improving the efficiency of your mass spectrometer. With over 150 replacement detectors to choose from, we can supply the replacement detector in a wide range of mass spectrometers, even if the instrument is no longer manufactured. Additionally, many of our detectors can be bought as complete repl…

PHOTONIS’ Advanced Performance Detectors (APDs) are plug-and-play electo-optic assemblies which provide a complete housing, facilitating manufacturing assembly, repair or replacement to mass spectrometers and other machines. Available for new machines or as replacement cartridges for existing models, over 200 types, with cartridge-mounted MCP, further simplifying additional repairs. ¶PHOTONIS Advanced Performance Detectors (AP…

PHOTONIS offers the widest and most technologically advanced variety of Time-of-Flight Detectors available. These patented detectors offer previously unobtainable levels of temporal resolution, dynamic range, and high mass detection sensitivity for TOF Mass Spectrometry. PHOTONIS' unique 2-Micron pore MCP provide the highest channel density of any MCP providing gains in excess of 5x106. PHOTONIS manufactures Time-of-Flight Det…

PHOTONIS is the industry leader in technology advancements for Microchannel Plates (MCPs). We offer a broad range of sizes, shapes and options to support a number of imaging applications. Our expertise across two production locations ensures continual research and development while ensuring our customers receive the customization and service for which we are known. For over thirty years, PHOTONIS has consistently set the stand…

The Finnigan vMALDI Ion Source system provides fast, automated MS and Data Dependent MS/MS analysis of digested protein mixtures in a single, rapid experiment. While LC/MS analysis times are typically 30 to 60 minutes, using the Finnigan LTQ with the vMALDI ion source generally requires less than a minute per sample enabling high throughput protein identification. Production: The Finnigan vMALDI Ion Source Thermo's new F…

With the addition of the highly flexible and versatile 3100 Mass Detector, Hitachi’s LaChrom Elite ® HPLC System further solidifies its position as the leader in chromatographic analysis for a wide range of applications. The LaChrom Elite® HPLC system, in combination with the Waters® 3100 Mass Detector, provides unmatched selectivity, sensitivity and throughput for improved laboratory productivity. Features Seamless inte…

You expect the fullest possible insight into your sample. compact delivers the highest quality of results without compromise. All specified performance parameters simultaneously delivered in a single run with no need for tuning or optimization is what makes compact unique. Full Sensitivity Resolution Having to choose between resolution and sensitivity on other instruments restricts depth to which you can understand your sample…

The TargetLynx™ Application Manager automates sample data acquisition, processing and reporting for quantitative results.It incorporates a range of confirmatory checks that identify samples that fall outside user-specified or regulatory thresholds. Identify Non-compliant Samples TargetLynx rapidly identifies and flags samples where: Analytes are above a specified maximum reporting level (MRL) Analyte confirmatory ion rat…

BiopharmaLynx™ automates the processing and interpretation of biopharmaceutical product LC/MS data, enabling you to characterize your products. Developed with biopharmaceutical thought leaders for confident characterization and optimized workflow, BiopharmaLynx™ leverages Waters' leading protein informatics expertise. Determine the identity, purity and stability of biopharmaceuticals, working with either peptide maps or intac…

The only comprehensive screening solution The Waters® Screening Platform Solution with UNIFI™ is the first and only comprehensive screening solution – target, identify, quantify, and review using a streamlined analytical workflow that enables more accurate results across a wide range of applications.The platform is holistically designed, combining world-class instruments, software, Waters’ Analytical Standards and Reagents, a…

Purpose-built Solution Achieves Reliable Results with Unparalleled Efficiency and Accuracy The Forensic Toxicology Screening Application Solution with UNIFI delivers the sensitivity, reproducibility, and ease-of-use necessary to perform broad screening techniques on complex biological samples to identify drugs of abuse and other toxicants of interest. Now, for the first time, you will be able to reliably report the presence o…

Making a dedicated and expensive GC-TOF-MS used infrequently for just a few samples a thing of the past. The GC-APCI II source enables GC coupling to any Bruker TOF or QTOF, trap or FTMS system originally designed for LC coupling.With its second generation GC-APCI source, Bruker offers the greatest flexibility and highest performance with a combined GC frontend and high-resolution MS system for confident ID of unknown compoun…