LC-MS Products & Reviews

Unraveling the complexity of disease

Transforming medicine with metabolomics

Decoding lipid-driven biology

Efficient workflows for busy laboratories

Metabolomics in nutrition, microbiome, and disease

SEQUEST Cluster is a complete, preconfigured proteomics solution that enables accelerated throughput of increasingly complex, multidimensional informatics.Product detail:The SEQUEST Cluster offers a scalable solution for computing the large volumes of data typical in most proteomics analyses using LC/MS. Protein database search times are dramatically reduced by harnessing the power of several processing units in one, increasin…

Enzymatic digestion of proteins in polyacrylamide gel slices and subsequent analysis of the peptides by mass spectrometry has become a routine procedure in protein analysis. In solution digestion protocols for bottom-up proteomics complement it. The DigestPro MSi automates all those procedures to achieve high throughput under controlled and reproducible conditions.

PHOTONIS Channeltron detectors provide the highest sensitivity due to superior signal collection and noise reduction, effectively improving the efficiency of your mass spectrometer. With over 150 replacement detectors to choose from, we can supply the replacement detector in a wide range of mass spectrometers, even if the instrument is no longer manufactured. Additionally, many of our detectors can be bought as complete repl…

PHOTONIS’ Advanced Performance Detectors (APDs) are plug-and-play electo-optic assemblies which provide a complete housing, facilitating manufacturing assembly, repair or replacement to mass spectrometers and other machines. Available for new machines or as replacement cartridges for existing models, over 200 types, with cartridge-mounted MCP, further simplifying additional repairs. ¶PHOTONIS Advanced Performance Detectors (AP…

PHOTONIS offers the widest and most technologically advanced variety of Time-of-Flight Detectors available. These patented detectors offer previously unobtainable levels of temporal resolution, dynamic range, and high mass detection sensitivity for TOF Mass Spectrometry. PHOTONIS' unique 2-Micron pore MCP provide the highest channel density of any MCP providing gains in excess of 5x106. PHOTONIS manufactures Time-of-Flight Det…

PHOTONIS is the industry leader in technology advancements for Microchannel Plates (MCPs). We offer a broad range of sizes, shapes and options to support a number of imaging applications. Our expertise across two production locations ensures continual research and development while ensuring our customers receive the customization and service for which we are known. For over thirty years, PHOTONIS has consistently set the stand…

The Finnigan vMALDI Ion Source system provides fast, automated MS and Data Dependent MS/MS analysis of digested protein mixtures in a single, rapid experiment. While LC/MS analysis times are typically 30 to 60 minutes, using the Finnigan LTQ with the vMALDI ion source generally requires less than a minute per sample enabling high throughput protein identification. Production: The Finnigan vMALDI Ion Source Thermo's new F…

With the addition of the highly flexible and versatile 3100 Mass Detector, Hitachi’s LaChrom Elite ® HPLC System further solidifies its position as the leader in chromatographic analysis for a wide range of applications. The LaChrom Elite® HPLC system, in combination with the Waters® 3100 Mass Detector, provides unmatched selectivity, sensitivity and throughput for improved laboratory productivity. Features Seamless inte…

You expect the fullest possible insight into your sample. compact delivers the highest quality of results without compromise. All specified performance parameters simultaneously delivered in a single run with no need for tuning or optimization is what makes compact unique. Full Sensitivity Resolution Having to choose between resolution and sensitivity on other instruments restricts depth to which you can understand your sample…

The TargetLynx™ Application Manager automates sample data acquisition, processing and reporting for quantitative results.It incorporates a range of confirmatory checks that identify samples that fall outside user-specified or regulatory thresholds. Identify Non-compliant Samples TargetLynx rapidly identifies and flags samples where: Analytes are above a specified maximum reporting level (MRL) Analyte confirmatory ion rat…

BiopharmaLynx™ automates the processing and interpretation of biopharmaceutical product LC/MS data, enabling you to characterize your products. Developed with biopharmaceutical thought leaders for confident characterization and optimized workflow, BiopharmaLynx™ leverages Waters' leading protein informatics expertise. Determine the identity, purity and stability of biopharmaceuticals, working with either peptide maps or intac…

The only comprehensive screening solution The Waters® Screening Platform Solution with UNIFI™ is the first and only comprehensive screening solution – target, identify, quantify, and review using a streamlined analytical workflow that enables more accurate results across a wide range of applications.The platform is holistically designed, combining world-class instruments, software, Waters’ Analytical Standards and Reagents, a…

Purpose-built Solution Achieves Reliable Results with Unparalleled Efficiency and Accuracy The Forensic Toxicology Screening Application Solution with UNIFI delivers the sensitivity, reproducibility, and ease-of-use necessary to perform broad screening techniques on complex biological samples to identify drugs of abuse and other toxicants of interest. Now, for the first time, you will be able to reliably report the presence o…

Making a dedicated and expensive GC-TOF-MS used infrequently for just a few samples a thing of the past. The GC-APCI II source enables GC coupling to any Bruker TOF or QTOF, trap or FTMS system originally designed for LC coupling.With its second generation GC-APCI source, Bruker offers the greatest flexibility and highest performance with a combined GC frontend and high-resolution MS system for confident ID of unknown compoun…

The Waters Metabolite Identification and Application Solution with UNIFI® is built to excel in identifying and characterizing metabolites, incorporating both qualitative and quantitative tools in both drug discovery and development.The UNIFI Scientific Information System brings ease and efficiency to routine processes to enable laboratories to rapidly derive results from complex data sets. In discovery, the system helps resear…

The Atmospheric Solids Analysis Probe* (ASAP) is a useful tool for the rapid direct analysis of volatile and semi-volatile, solid and liquid samples using atmospheric pressure ionization.The ASAP technique utilizes the heated nitrogen desolvation gas to vaporize the sample and a corona discharge for sample ionization. This allows low polarity compounds not amenable to ESI, APcI and APPI to be ionized with a high degree of sen…

Variable-energy electron ionization source technology for GC–MS

Trypsin NB with unique resistance to autolytic digestion  for in-gel digestion and mass spec

Our industry leading  bioanalytical solutions have helped our clients develop  new peptide therapeutics  to improve the quality of life. Combining our experience and cutting-edge technology, we have has developed and validated methods using LC-MS/MS to quantify levels of peptides in plasma at levels as low as 10 pg/mL.

The SilverQuest™ Silver Staining Kit provides a rapid and easy method to silver stain proteins and DNA in polyacrylamide gels. Silver staining allows detection of most proteins since it is 30-fold more sensitive than staining with colloidal Coomassie® G-250. The SilverQuest™ Silver Staining Kit is specifically designed to provide sensitive silver staining compatible with mass spectrometry analysis. Ideal for rapid preparati…