Combinatorial Chemistry Products & Reviews

Integrated ASO development from sequence design and chemistry selection to preclinical PK/PD, safety, delivery (e.g., GalNAc), and CMC—supporting gapmer and steric-blocker approaches to advance programs efficiently toward IND.

The Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library serves as a leading resource to expedite the discovery of high-quality antibodies with exceptional specificity. Our library makes efficient identification of optimized drug candidates possible through the use of advanced humanization and randomization technologies, together with a strong high-throughput screening platform.

Comprehensive circRNA services including design, circularization (e.g., ribozyme/intron-mediated), purification, and analytics to deliver stable, translation-competent RNA with improved durability—supported by process development for research and translational programs.

The HuScL-6 Human Single Chain Antibody Library is a state-of-the-art resource for efficient, high-quality antibody screening. Designed to meet the diverse needs of researchers, this library provides access to a rich pool of scFv antibodies derived from human naïve antibody genes.

End-to-end viral vector design and construction covering vector/serotype selection, expression-cassette optimization, cloning, packaging, purification, and QC. Supports AAV, lentivirus, adenovirus, HSV, vaccinia, and baculovirus with scalable production and documentation for in vitro/in vivo studies and IND-enabling work.

Twist Multiplexed Gene Fragments are double stranded gene fragment sequences of up to 500 base pairs in length that are delivered as a pool instead of one fragment per well matrix.

Vapourtec offers a range of world class peptide synthesizer systems offering fast flow solid phase peptide synthesis from 0.05 mmol to 30 mmol.

ISOAPI-D™: Built Specifically for the Next Generation of Deuterated Reagents in Pharmaceutical Development

Stable Isotope-labeled Gases and Packaging Options

Stable Isotope-Labeled Materials for Peptide Synthesis

IDEAL FOR ORGANIC AND AQUEOUS SYNTHESES

Assay (GC): ≥ 99.0%

Sino Biological provides comprehensive ADC development and production solutions, covering early discovery, process development, preclinical studies, and clinical research, to fully support clients throughout the ADC development process.

GenScript provides targeted lipid nanoparticle (LNP) formulation services for precision RNA delivery applications, including immune cell engineering, in vivo CAR-T, gene editing, and therapeutic development. By combining optimized LNP formulations with ligand-mediated targeting strategies, the GenScript platform is designed to improve delivery efficiency, targeting specificity, and translational potential for advanced RNA ther…

Stable Isotope-labeled Elements and Compounds

SynPhase Lanterns are the latest generation of grafted products optimized for small organic molecule and peptide synthesis.The SynPhase Lantern is cylindrical in appearance and is available in three different sizes, L-series, D-series and A-series with physical dimensions as shown in the table below. These properties make the SynPhase Lantern compatible with a wide range of reaction vessels and synthesizers.

HBPS provides both research and cGMP monoclonal antibody production.

Do you need interesting and unique building blocks for you small molecule combinatorial program? If you look at our 3500 In-House designed and externally acquired building blocks (from contract chemists) we are sure you will agree that this is a unique collection. These building blocks cannot be found in the major catalogues.

StarDrop is a suite of software that helps you to deliver optimally balanced, effective drugs - fast StarDrop works by evaluating complex data, which is often uncertain because of experimental variability or predictive error. In scoring this data, it brings confidence and intuitive simplicity to decision-making: guiding and validating the direction you take and which compounds you prioritise. Its instantly interactive tools t…

Safe, Ecological, Waterproof.In order to protect the extraordinary quality of our SeccoSolv® dried solvents, we offer a fully sealed stainless steel barrel system for extremely water-sensitive applications that keeps water out even more effectively. Unlike our standard stainless steel barrels, the fully sealed barrel system requires no adapters but uses fast connectors that fit onto the rim of the barrel quickly and easily.…

The FIAstar™ 5000 System is used for the automatic wet chemical analysis of nutrients and other parameters in water, soil and wine, as well as in meat or other food products. Single or multiple parameters can be analysed sequentially using just one Analyser module and Plug & Analyse Method Cassettes. The modular system can be expanded for the simultaneous determination of up to three parameters.The Plug & Analyse concept ensur…

Alfa Aesar offers a full range of precious metal salts and solutions manufactured to stringent specifications. Homogeneous catalysis provides an excellent choice where highly specific reactions are desired including chiral transformations. Our homogeneous catalysts can be used in a wide range of chemical transformations. Supported (heterogeneous) precious metal catalysts are used in a variety of reactions including hydrogena…

The AutoLAB has been design by chemists for chemists and features a range of innovations to make it easy-to-use, to reduce training time and the need for specialist users to a minimum. Manual or software controlled Upgradeablity built-in by design Tool-less couplings. It is HEL's industry-leading WinISO software control system that puts ""Auto"" into AutoLAB. WinISO is feature-packed, allowing for standard datalogging and para…