UHPLC and HPLC Products & Reviews

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High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Foxy® R2

Teledyne Labs

The two-rack Foxy R2 fraction collector can be adapted to a broad spectrum of applications. The units can distribute fractions into 96 well microplates, standard tube sizes, and bottles. For essentially unlimited volumes, funnel racks can direct fluids to any collection vessel or downstream process. 

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RediSep ® Gold ® ​​ C8​

Teledyne Labs

RediSep Rf Gold C8 reversed-phase columns are packed with 20–40 µm spherical bonded silica, providing improved separation. Achieve near prep-HPLC results with greater sample recovery to easily purify up to gram-scale on your Flash system. Increased pore size optimized for purification of larger molecules like peptides and proteins.

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SkillPak 1 and 5 mL pre-packed columns

Tosoh Bioscience

SkillPak 1 (0.7 cm ID x 2.5 cm L, CV 1 mL) and 5 (0.8 cm ID x 10 cm L, CV 5 mL) pre-packed columns offer a reproducible and efficient solution for screening and initial developing of purification methods for biomolecules. SkillPak 50 and 200 mL pre-packed columns are the best solution for seamless scale up of methods developed on SkillPak 1 and 5. 

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SkillPak 50 and 200 pre-packed columns

Tosoh Bioscience

SkillPak 50 (2.5 cm ID x 10 cm L, CV 50 mL) and 200 (5 cm ID x 10 cm L, CV 200 mL) pre-packed columns offer a reproducible and efficient solution for developing purification methods for biomolecules. They are the best solution to scale up methods developed on SkillPak 1 and 5 mL pre-packed columns.

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Closed Barrel - simple storage for dried solvents

Merck KGaA, Darmstadt, Germany

Safe, Ecological, Waterproof.In order to protect the extraordinary quality of our SeccoSolv® dried solvents, we offer a fully sealed stainless steel barrel system for extremely water-sensitive applications that keeps water out even more effectively. Unlike our standard stainless steel barrels, the fully sealed barrel system requires no adapters but uses fast connectors that fit onto the rim of the barrel quickly and easily.…

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SeQuant® ZIC®-cHILIC for HPLC and LC-MS separation of polar hydrophilic compounds

Merck KGaA, Darmstadt, Germany

This new zwitterionic stationary phase with phosphorylcholine functional group provides you with complementary selectivity for easier method development for substances that have been difficult to separate by previous types of HPLC columns operated in reversed-phase or HILIC mode. The selectivity features of SeQuant® ZIC®-cHILIC are especially beneficial for negatively charged polar compounds such as nucleotides and organic…

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Fast Separation of Pharma Samples

Merck KGaA, Darmstadt, Germany

Fast separation of pharma samples: 10 compounds in 2 minutes.   As in all industries, greater productivity has become increasingly important in the field of pharmaceuticals. Consequently, there is a growing demand for fast and ultra-fast separations as well as higher sample throughput. To answer these requirements, Merck Millipore offers the perfect combination for separation speed and peak symmetry: Purospher® STAR UHPL…

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Chromabolt™ Prepacked Columns

Merck KGaA, Darmstadt, Germany

Chromabolt™ is a family of pre-validated columns prepacked with EMD Millipore chromatography resins, designed for early clinical stage manufacturing. Available in 3 sizes – 10, 20 and 32 cm inner diameter (i.d.), these prepacked columns free up end users valuable time and resources by eliminating manual packing and cleaning. With Chromabolt™ prepacked columns, you can spend your time on manufacturing your products and not on…

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LiChrosorb® Bulk Packing Material

Merck KGaA, Darmstadt, Germany

A successful packing material from the start: LiChrosorb® is one of the most successful and reliable packing materials used in HPLC for more than 25 years and documented in literature in the form of several thousand applications. The totally porous irregular particles are finely classified in the 5, 7 and 10 µm range. LiChrosorb® offers the complete programme of non-polar derivatives (RP-8, RP-18, RP-select B) polar derivativ…

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LiChrospher® Bulk Packing Material

Merck KGaA, Darmstadt, Germany

Spherical silica carrier for constant results on high level: LiChrospher® are reliable and versatile traditionally produced spherical silica carrier. LiChrospher® silica carrier are available with different modifications. For the LiChrospher® RP-phases a selectivity and performance guarantee makes sure that these parameters remain constant form batch to batch and from year to year. The polar modified phases LiChrospher® CN, L…

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