Preparative Chromatography Products & Reviews

Highly flexible chromatography system for process scale-up and large-scale manufacturing

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.

YMC HT Glass Columns are specially designed to accommodate the stringent requirements of high-temperature liquid chromatography applications. Capable of performing efficiently at temperatures up to 70 °C, these columns are perfectly suited for a broad spectrum of purification tasks, particularly in biochemical liquid chromatography (BioLC), where high temperatures are pivotal.

BioPro IEX, YMC's strong ion exchange material are based on a hydrophilic polymer which provides low non-specific adsorption and high recoveries. Porous and non-porous polymer beads are available for high loadability and throughput.  

With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.

From laboratory to pilot scale, YMC offers reliable, high quality glass columns for all kind of application areas.

YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling.

Does your application require customised pilot columns? With YMC Pilot columns, customised versions can be constructed to address your needs. Of course standard dimensions are available, too!

BioPro IEX and BioPro IEX SmartSep resins are specifically designed for biochromatography. They are available as a strong anion exchanger (BioPro IEX Q) and a strong cation exchanger (BioPro IEX S). The resins are based on a hydrophilic polymer matrix, with a particle size of 10 µm, 20 µm, 30 µm and 75 µm.

Highly robust hybrid silica material for the purification of proteins, peptides and oligonucleotides, which combines mechanical strength and pH stability. The larger pore size makes YMC Triart-Prep Bio200 C8 the ideal choice for the purification of mid-size to large biomolecules.

The 1260 Infinity II Preparative Fraction Collector is optimized for laboratories performing semipreparative-scale purification of milligram to low gram quantities with typical flow rates between 4 and 100 mL/min. The module features the full set of collection modes and is compatible with a wide variety of trigger sources. SBS plates and four different tube sizes with various lengths are supported.

Agilent Lewis Antigen (formerly ProZyme) standards are available in labeled and unlabeled forms.

PL-SAX strong anion-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

PL-SCX strong cation-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

The PLRP-S media, rigid poly(styrene/divinylbenzene) particles, are available in a range of pore sizes for small molecule, synthetic biomolecule and macromolecule purification. 

The VariTide RPC columns and media are part of the VariPep Peptide Solution.

The 1220 Infinity II Analytical-Scale Purification System is an affordable, entry level, high-quality system based on proven technology. Four integrated, all-in-one configurations are available to get you on the fast track to efficiency and maximum return-on-investment.

The 1260 Infinity III Analytical-Scale LC Purification System is the most flexible and versatile solution for compound isolation within the InfinityLab LC purification portfolio.

The 1290 Infinity III Analytical-Scale LC Purification System is a preparative ultrahigh-performance liquid chromatography (UHPLC) system that embodies the future of UHPLC compound isolation.

The 1260 Infinity II Manual Preparative LC System is an easy-to-use, entry-level solution for LC purification with upgrade possibilities to do routine purification of milligram up to gram scale quanities of materials. This binary gradient system delivers dynamic flow rates up to 50 mL/min at 420 bar, equipped with a manual injection valve. The system achieves outstanding performance and reliability day-in and day-out, and is t…

The 1260 Infinity II Preparative LC System is an easy-to-use workhorse for automated sample injection when gradient elution is required for sample purification. The binary gradient pump deliver flow rates up to 50 mL/min for purification up to 30.0 mm id columns. This system is tailor-made for routine, high-throughput, laboratory-scale purification when milligrams to grams of starting material are available.

The 1260 Infinity II Preparative LC/MSD System can be configured with UV and MS detectors as well as multiple fraction collectors to meet your purification needs. Automated sample injection increases daily sample throughput and mass-based fraction collection maximizes purity and minimizes re-analysis.

The 1290 Infinity II Preparative LC System is designed for the purification laboratory that needs increased daily throughput by offering automated sample injection and fraction collection, smooth control of LC valves, and flexible access to up to four analytical columns and six preparative columns.

The 1290 Infinity II Preparative LC/MSD System enables high-throughput purification, delivering high-quality compounds, for example, for biological screening, an important part of drug discovery.

The 1290 Infinity II Autoscale Preparative LC System is a scalable, workflow-based solution that facilitates automated scale-up from analytical method scouting to optimized purification.