Enzymes Products & Reviews

Tyrosine kinase inhibitor; Inhibits ABL, SRC, LCK and YES

Notch pathway inhibitor; Inhibits ?-secretase

Inhibits EGFR and VEGFR

Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK2

BMP and AMPK pathway inhibitor; Inhibits ALK2, ALK3, ALK6, and AMPK

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

Adenosine deaminase and PDE2 inhibitor

mTOR pathway inhibitor; Inhibits FKBP-12

Epigenetic modifier; Inhibits SIRT1 histone deacetylase

RHO/ROCK pathway inhibitor; Inhibits ROCK2

Calcineurin/NFAT pathway inhibitor; Binds FKBP-12

Serotonin reuptake inhibitor

Epigenetic modifier; Inhibits histone acetyltransferases (HATs) p300 and pCAF

PI3K/AKT pathway inhibitor; Inhibits Class I PI3Ks

Tyrosine kinase inhibitor; Inhibits EGFR

RHO/ROCK pathway inhibitor; Inhibits ROCK1 and ROCK2

CSF-1 pathway inhibitor; Inhibits cFMS

Protein kinase inhibitor; Inhibits PKA, PKC, and PKG

Hedgehog pathway inhibitor

Inhibits autophagy and heme polymerase

BET family inhibitor; Inhibits BRD2, BRD3, and BRD4

cAMP pathway activator; Inhibits cyclic nucleotide phosphodiesterases

Tyrosine kinase inhibitor; Inhibits ABL, PDGFR, and KIT

WNT pathway activator; Inhibits protein phosphatase PP2A

SCF/c-KIT pathway inhibitor; Inhibits c-KIT