UHPLC and HPLC Products & Reviews

The 1220 Infinity II LC is an integrated system for routine HPLC analysis in analytical and QA/QC labs. Based on the proven technology of the InfinityLab LC Series, the system's high quality and performance help you achieve maximum return on investment and lowest cost of ownership from day one.

Reversed Phase Method Development that's Simple, Fast, Effective, and Universal!•Boasts the widest range of reversed phase selectivity in the industry.•Simplifies column selection down to 4 unique stationary phases.•Employs orthogonal selectivity to speed up effective method development.•Maximizes efficacy of your column screening systems.•Fits any HPLC or UHPLC instrumentation. Restek Ultra Selective Liquid Chromatography™ (…

Switch to a Raptor HILIC-Si LC column when you need more retention and resolution of hydrophilic, polar analytes. HILIC silica column designed for increased retention of polar compounds without ion-pairing reagents. 2.7 μm Raptor core-shell particles provide the speed of SPP, with greater efficiency and capacity than 5 μm particles. Ideal for increasing sensitivity and selectivity in LC-MS analyses. Fully compatible with both…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications. This exceptionally stable C1 phase features our least-retentive reversed-phase hydrocarbon packing. Stationary Phase Category: trimethylsilane (L13) Ligan…

ChromXP columns optimize performance, ease of use, and reliability of the SCIEX M5 MicroLC, MicroLC 200 Plus and NanoLC 400 systems. ChromXP columns ensure optimum separation and long term stability.  

High purity, Type B, spherical silica support. 100A pore size. 1.8um, 3um, & 5um partical sizes. Variety of stationary phases.

The EXP® Guard Column cartridge system is rated to 15,000 psi with hand-tight replaceable cartridges. This unique design connects directly to any UHPLC column with the auto-adjusting Titanium Hybrid Ferrule and EXP® Fittings, providing repeated zero-dead-volume connections and easy adjustability between various column types. Free-Turn¨ architecture allows the user to change cartridges by hand without breaking fluid connections…

The Biotage® Selekt family of flash chromatography systems combines patented gradient development software with flexible fractionation strategies for streamlined purification.

TSKgel Amide-80 and TSKgel NH2-100 HILIC columns from Tosoh Bioscience are first class columns when it comes to separations of hydrophilic compounds like peptides, carbohydrates, polar natural substances, amino acids, oligonucleotides, organic polar acids and bases, even proteins.

HPLC column

Widely considered the premium columns for analyzing biopolymers by GFC, TSKgel G2000SWXL, 5 μm columns are an excellent choice for small proteins and peptide separations.

The TSKgel Alpha-4000 column is packed with rigid, porous polymer beads which show minimal shrinkage or swelling in polar organic solvents (methanol, acetonitrile, DMSO, isopropanol, THF, and HFIP). This column is stable in a wide variety of organic solvents at concentrations up to 100%.

The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.

TSKgel STAT columns were designed to increase throughput for high efficiency separations of biomolecules. The nonporous, hydrophilic base material provides superior performance at reduced analysis time.

Silica-based columns are stable and efficient but unsuitable for alkaline analyses due to the silica matrix's weakness under high pH. InertSustain C18, with its novel surface-modified silica, overcomes this limitation. It retains Inertsil's benefits—low back pressure, superior inertness, high efficiency, consistent performance, and wide solvent compatibility—while enabling analyses over a broad pH range.

The Biochrom 30+ Amino Acid Analyzer is trusted by hospitals, reference labs, pharmaceutical and industrial labs worldwide. It accurately detects and quantifies amino acids and their derivatives in complex samples. Applications include: detection and monitoring of in-born errors of metabolism, PKU testing, clinical analysis, proteomics, drug synthesis, infusion fluids, and quality control. The system is based on cation exc…

The 1525 and 1525 with EF heads are integrated, high-pressure, binary HPLC pumps that feature on-board pulse dampening and efficient mixing. Their pulse-free solvent flow, from analytical to semi-preparative flow rates, makes them ideal for use with highly sensitive detectors. Designed for use with 2 to 4.6 mm I.D. columns in routine LC and LC/MS applications, these pumps have a programmable flow-rate range of 0.00 to 10.00 mL…

CHIRAL TECHNOLOGIES offers an expanded line of immobilized polysaccharide chiral stationary phases (CSPs), CHIRALPAK IA™, IB™, and IC™. These immobilized CSPs allow the use of a highly extended range of solvents and offer new separation selectivities relative to conventionally coated CSPs. All three are based on high-efficiency 5-µm diameter spherical silica (or 20-µm for scale-up to semi-preparative and preparative applicatio…

Amino Acid Analysis Columns

First generation Hybrid particles for high pH stability

ZirChrom Separations Inc. (Anoka, MN) provides a full line of zirconia-based HPLC columns for chromatographic method development.  ZirChrom HPLC columns offer unique selectivity, exacting reproducibility, high efficiency and ultra-stability.  ZirChrom columns have proven utility over a wide range of pharmaceutical compounds.  The columns may be used at both ambient and elevated temperatures (which helps enhance LC/MS sensitivi…

An integrated HPLC system that works as hard as you do, available with push-button mass detection for the chromatographer. The Alliance™ HPLC System is the flexible and reliable workhorse that meets your fundamental HPLC separation requirements. The system has been continually expanded and perfected to accommodate an enormous range of real-world analytical challenges, culminating in today’s new industrial design which signi…

A Sensitive solution for HPLC, fast-LC and CE systems High Sensitivity: 10 times to 100 times greater than conventional fluorescence and up to 100,000 times more sensitive than UV detection. Versatility: 14 interchangelable different lasers availables for any application Modularity : Adaptable to CE and HPLC systems including Fast-LC, Capillary LC and nanoLC.Selectivity: Low noise and interference molecules will be detected.…

Exceptional peak symmetry and resolution Based on next-generation ultra pure silica Outstanding pH stability Ideal first choice for new method developmentProduct detail:Hypersil GOLD columns are a new LC and LC/MS column offering unsurpassed peak shape. Based on highly pure silica, Hypersil GOLD columns provide the ultimate in symmetrical peaks, even when analyzing compounds that give notoriously poor peak shape on traditional…

The Chromaster Analytical HPLC System from Hitachi has established new limits in Performance, Ease-of-Use, and Robustness. Innovative low-pressure gradient mode, “High Frequent Mode,” and Hitachi’s proprietary real-time feedback control system greatly suppress liquid pulsation resulting in unparalleled retention time and gradient reproducibility. The Hitachi Chromaster is also available with 60 MPa maximum pressure.