Drug discovery > Target Discovery Products & Reviews

Immunodensity negative selection cocktail

Growth-regulated oncogene beta

JAK/STAT pathway inhibitor; Inhibits JAK1, JAK2, and JAK3

Epigenetic modifier; Inhibits Jumonji histone demethylases

RUNX1 transcriptional activator; Binds filamin A

WNT pathway activator; Inhibits GSK3ß

mTOR pathway inhibitor; Inhibits mTORC1 and mTORC2 complexes

NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)

WNT pathway inhibitor

Activates ß-3 adrenergic receptors

Tyrosine kinase inhibitor; Inhibits EGFR and HER2

BMP pathway inhibitor; Inhibits ALK1, ALK2, ALK3, and ALK6

p38 MAP kinase (MAPK) inhibitor

PI3K/AKT pathway inhibitor; Inhibits PI3K

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK5

Notch pathway inhibitor; Inhibits ?-secretase

AMPK activator; Mitochondrial respiratory chain complex 1 inhibitor

Antibiotic with anti-inflammatory and neuroprotective properties

Antibiotic; Double-stranded DNA alkylating agent

Aurora kinase pathway inhibitor; Inhibits aurora kinase A

Inhibits NEDD8-activating enzyme

Inducer of neural differentiation

For culture of human, mouse, and rat epithelial stem cells

Cell culture medium for establishment and maintenance of mouse hepatic progenitor organoids

For differentiation of human monocytes into dendritic cells