Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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CellBase CT - for ex-vivo expansion of autologous cell therapy products

TAP Biosystems

CellBase CT is a new automated system designed for ex-vivo expansion of autologous cell therapy products. Developed with leading cell therapy organisations, CellBase CT scales up existing manual cell culture processes in T-flasks, enabling manufacture of cell therapy products derived from a wide range of cell types, including hES, iPS and adult stem cells. CellBase CT automates:CellBase CT automates the maintenance and expansi…

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ProReveal Test

Synoptics Health

Fluorescence Protein Detection Test ProReveal is a highly sensitive fluorescence-based patented protein detection test for checking the presence of residual protein on surgical instruments after going through a washer disinfector process. This cost-effective test (conforms to BS EN ISO 15883-1) delivers objective, visual and measurable results, removing any doubt as to whether a decontaminated instrument is safe for reuse. Ke…

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Tube Auditor™

Brooks Life Sciences

The Tube Auditor™ measures sample volumes and detects precipitate using high-speed vision technology. It gives confidence in the quality of your samples (at both collection and output) and helps reduce downstream costs and waste, which can arise from empty wells and precipitated samples. Applications include Compound Management, High Throughput Screening and Biobanking. 

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MultiPep RSi

Intavis Inc.

The MultiPep RSi is a fully automated high throughput multiple peptide synthesizer based on a pipetting robot. Utilizing exchangeable modules, the MultiPep RSi can be configured to enable the synthesis of small scale peptide libraries, membrane bound peptide arrays (SPOT method), specialty peptides or PNAs, as well as high quality peptides in large scales up to 10 mmol. Due to this flexibility, the instrument can take the pl…

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MultiPep CF

Intavis Inc.

The MultiPep CF is a fully automated peptide synthesizer with a unique column module that allows the synthesis of long and difficult sequences. During the synthesis, reagents are continuously circulated and real time UV monitoring enables the automatic optimization of reaction parameters like deprotection, coupling times, and wash steps. This leads to a greater coupling yield, superior peptides, and also saves time and reduc…

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HyCryo™ Cryopreservation Media

Thermo Fisher Scientific

Thermo Scientific™ HyCryo Cryopreservation Media is a serum-free, animal origin-free product intended for cryogenic storage of your standard cell lines. HyClone™ HyCryo media is a serum-free, animal origin-free product intended for cryogenic storage for your standard cell lines. HyCryo gives you the recovery that you want from your cells with peace of mind knowing that your precious cells are faithfully preserved for your futu…

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HyCryo-STEM™ Cryopreservation Media

Thermo Fisher Scientific

Thermo Scientific™ HyCryo-STEM is designed specifically for stem cells, with a serum-free formulation that maintains differentiation potential and minimizes spontaneous differentiation of stem cells. HyCryo-STEM provides impressive cell recovery and post-thaw growth of pluripotent stem cells (ESC and iPSC) and neural progenitor cells such as mouse cortical stem cells (MCSCs) and rat cortical stem cells (RCSCs). The serum-free…

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Pippin Link Group Controller

Sage Science

The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.

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WHEATON® Integrated Biobanking System

WHEATON

WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…

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Soxtherm 416

Lab Synergy

Gerhardt has created a complete line of Soxtherm models, creating the ideal opportunity to have a state of the art lab for Extraction systems. One of the most impressive units in the line is the Soxtherm 416, capable of six extraction places capable of holding both small and large beakers. The unit is capable of nearly all analytical areas in fat determination and sample preparation specifically: milk, cereal, meat, oil, fruit…

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Ion Mobility Spectrometer (IMS) Analyzer

Photonis

The new PHOTONIS Ion Mobility Spectrometer (IMS) Analyzer is a complete integrated assembly for simplified IMS analysis that features high resolving power (64-150) in a compact design. The unit combines PHOTONIS’ patented Resistive Glass products with a new robust ion gate technology to create an IMS analyzer which improves resolution and simplifies serviceability. Key components of the IMS Analyzer are made from Resistive Gla…

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RFP-Trap®

Chromotek GmbH

RFP -Trap® - use your fluorescence fusion as tag for biochemical studies Curiously RFP, a widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited RFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses. Superior results in a fraction of the time The ChromoTek RFP-Trap® overcomes these pro…

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GFP-/RFP Booster

Chromotek GmbH

GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…

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Chromobodies®

Chromotek GmbH

Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…

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GST Toolbox

Chromotek GmbH

Fusion of proteins to Glutathione S-Transferase (GST) of Schistosoma japonicum is a common technique to increase solubility and expression level of a protein. Furthermore, GST-tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. GST-Trap The GST-Trap is a highly specific and robust GST-binding protein coupled to ma…

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Epigenetic Toolbox

Chromotek GmbH

DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…

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Cell Cycle Toolbox

Chromotek GmbH

Proliferating cell nuclear antigen (PCNA) is a homotrimeric ring-shaped protein that encircles DNA and acts as a loading platform for multiple, transiently interacting factors participating in various DNA transactions. PCNA plays a key role in DNA replication, repair, cell cycle regulation, and post-replicative transactions like DNA methylation and chromatin remodeling. All these cellular processes are regulated by a complex n…

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Cell Organelle Toolbox

Chromotek GmbH

Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…

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aurora Elite ICP-MS

Bruker CAM

Inductively Coupled Plasma Mass Spectrometer (ICP-MS) The Science of sensitivity Bruker's ICP-MS is famous for its innovative and unique technology and has now been further refined to meet the ever increasing demands of latest application and laboratory requirements. Bruker's aurora M90 continues to be the workhorse for the routine laboratory, now with additional and improved characteristics. In addition to the aurora M90, Bru…

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Disposable Cuvettes for Spectroscopy

Kartell S.p.A.

Disposable cuvettes for spectrophotometry, optical PS visible range cuvettes, UV Grade PMMA cuvettes. Standard and semi-micro disposable cuvettes for spectroscopy made of optical PS and PMMA UV grade optical windows to achieve optimal transmittance through spectral range from 340 to 800 nm (OPS) an from 280 to 800 nm (PMMA UV qrade). The engineering and quality control determine the reproducibility of the cuvettes. These are s…

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VenaT4 Biochip

Cellix Ltd

The VenaT4™ biochip model combines Cellix's proprietary microfluidic flow technology for cell recruitment under shear stress with traditional transwell chamber models. Used to investigate and quantify cell recruitment to various ligands in the presence of chemoattractants contained within the microwells mimicking tissue and / or injury sites. The biochips contain 4 microcapillaries in parallel, each with an embedded microporo…

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FlowCellect™ Human NK Cell Characterization Kit

Merck

The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…

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DART® Ion Mobility Spectrometer

Photonis

DART® Ion Mobility Spectrometer The new DART® Ion Mobility Spectrometer is a completely integrated benchtop instrument equipped with Resistive Glass technology and improved performance. It provides DART-IMS analysis of solid, liquid or gas analytes quickly and easily for use in homeland security, pharmaceutical or laboratory applications. Sample preparation is easy, and identifiable results can be seen in less than 10s. The…

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