Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
An easy way to assess tag accessibilityThe production of fusion proteins often raises the issues not only of their structural integrity after isolation, but also of the accessibility of the associated tag. In the case of GST or 6HIS tagged proteins, this verification can be achieved with HTRF® GST and 6HIS check kits. These two assays are competitive immunoassays in which the anti-GST or anti-6HIS Cryptate conjugates bind dire…
A new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic advantages of an HTRF® system: totally homogeneous, detection via fluorescence, signal stab…
A team of experts for outsourcing your assay developmentsOur Service Team at Cisbio international is highly trained in protein chemistry and fluorescent technology, and offers you its expertise in assay development to build HTRF® assays adapted to your specific targets or to convert existing assays to HTRF® technology.Assays may be developed using HTRF® toolbox reagents, custom labeled molecules or a combination of both. Most…
Rapid Analysis of Multiple 2D Gel Sets DYMENSION 2 has all the features of DYMENSION 1 but has the added ability to detect and compare protein spot maps in multiple gel sets. The software offers many background correction and noise filtering features including a SYPRO® Ruby filter, which can detect and automatically remove spots caused by SYPRO® Ruby crystals adhering to the gel, thus saving users valuable time editing the…
Quick and Easy Analysis of all 2D Gel Applications The exciting DYMENSION 3 software has all the functionality of DYMENSION 2, so can be used to analyse multiple gel sets. In addition, DYMENSION 3 is capable of analysing multi-stained fluorescent gel images stained with up to three contrasting fluorescent labels, for example, Cy™2, Cy™3 and Cy™5. This feature allows users to analyse multiple sets of any type of 2D protein…
VeroFect™ is a powerful reagent dedicated to the transfection of Vero cells. This lipid -based transfection reagent is issued from the revolutionary Tee-Technology and achieves up to 50-55% transfection efficiency. The complexes formed by DNA and VeroFect™ reagent have an exceptional capacity in destabilizing cell membranes, allowing the delivery of important DNA amounts into cells. VeroFect™ was specifically designed to obtai…
Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during fluorescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…
The REMP Portrait Heat Sealer is a completely electro-mechanical, thermal sealing instrument that does not require any air or vacuum to operate. This versatile and efficient instrument accommodates deepwell, assay, PCR, and standard microplates with only a minor adapter change. The REMP Portrait Heat Sealer uses any of the various rolls of REMP’s Thermo-Seals, most of which are resistant to DMSO, as well as, other solvents and…
Very economical untreated PVC microplates for solution-based assays, serial dilutions, and general storage applications Well volume of 250 µL; recommended working volume of 50 to 150 µL Lids are not available
High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity of approximately 500ng of mouse IgG/cm2 Ideal for immunoassays Certification results for each lot are made available upon request by contacting local Corning Life Sciences office Recommended working volume of up to 75 to 200 µL Conforms to standard microplate footprint and dimensions Wi…
Reusable orange polycarbonate box holds 81 cryogenic vials in a 9 x 9 array For use with 4 - 5 mL vials Ridges on sides of box make them easier to grip while wearing gloves
The SampleScan1000's combination of a 2D tube reader and LCD display, make this one of the most intuitive single tube scanners available. Place a tube on top of this unit and it will display the tube's ID number on the easy to read LCD. A linear bar code scanner is easy to integrate with the SampleScan 1000 software to capture additional 1D bar code data associated with 2D bar coded tubes. In addition, the SampleScan1000'…
digestec DAB-2/3, to Digest the Hardest Samples. The traditional “stainless steel bomb” with its PTFE insert is being increasingly replaced by the microwave for most routine applications. However, when it comes to difficult-to-digest samples such as silicon carbide or alpha-aluminium oxide, such systems remain of inestimable value to users. The great advantage of these systems lies in the fact that the digestion period can…
The program "Genom 2005" is a feature rich and user friendly tool to analyse array-experiments.Key Features:Analyse all AffyMetrix-Arrays (cDNA-Arrays or similar technologies could easily be integrated as well) Normalisation of Raw-Data Many additional gene information (official Gennames, Location, Function prediction, Sequences, Database-references (Gene-Ontology, InterPro, SwissPROT ,EMBL, ENSEMBL, LocusLink, OMIM, GeneBank.…
The Freedom EVO Nucleic Acid Sample Preparation workstation is a fully scalable, flexible system enabling automated nucleic acid purification for RNA, mRNA, gDNA and plasmids for a wide range of downstream applications.
The customized applications group specializes in realizing a broad range of tailor made research application solutions. If your automation needs the capabilities of a Freedom EVO® or requires a combination of multiple Freedoms, then a system designed from the customized applications group is the right solution for the next step in the automation upgrade path. It can be configured for higher capacity and throughput needs for co…
The Freedom EVO Nucleic Acid Normalization workstation enables straightforward automation of DNA quantitation, dilution and normalization protocols.
Tecan has partnered with GE Healthcare to develop an automated solution for screening of best producing clones, using MultiTrap plates on the popular Freedom EVO platform.
The Freedom EVO Protein Crystallography workstation is a highly flexible, fully scalable liquid handling platform that can be configured for semi- or complete automation protein crystallography experiments.
The flexible Freedom EVO platform offers numerous options for automated sample preparation processes, and can be tailored to specific laboratory needs.
Fully automated hit-picking on the Freedom EVO® The Freedom EVOware Hit-Picking Wizard extends the functionality of Freedom EVOware for the set-up of hit-picking and cherry-picking applications without the need for custom software. Integrating seamlessly into Freedom EVOware’s intuitive graphical user interface, the wizard leads you through selecting source & destination labware and reduces set-up time. Plate maps are graphic…
The Freedom EVO platforms deliver precision liquid handling, easy-to-use robotics and advanced process control for ADME processes.
High Throughput Bulk Reagent Dispenser that is Accurate - Affordable - Flexible - Fast Dual plate dispenser for 96 and 384 well plates UltraSpense 2000 is the answer to the increasing demand for an automated yet affordable dispenser for 96 and 384 well microplates. High accuracy and precision dispensing into deep well or low profile microplates, coupled with low dead volume and easy programming makes UltraSpense 2000 the i…
For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill is designed for lysis of mammalian blood, serum, or plasma samples, and the stabilization of nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or aft…
For use with:Cat. No. 03 172 627 001 MagNA Pure LC mRNA Isolation Kit II (Tissue) orCat. No. 03 330 591 001 MagNA Pure LC RNA Isolation Kit III (Tissue) For general laboratory use. The MagNA Pure LC RNA Isolation Tissue Lysis Buffer – Refill is designed for lysis and homogenization of fresh frozen tissue samples using a tissue homogenizer (see the MagNA Lyser Instrument) stabilization of total RNA and mRNA within samp…
