Drug discovery > Target Discovery Products & Reviews

Unlock deeper insights into tissue organization and cellular interactions with Crown Bioscience’s spatial biology and digital pathology services, featuring advanced imaging, automated analysis, and high-throughput biomarker screening for applications in cancer research, immunology, and more.

OrganoidXplore™, Organoid Panel Screening Service

Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.

Automated filtration and filling system designed to accurately and aseptically aliquot bulk product into multiple biocontainer bags or bottles.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.

Sirius T3 measures pKa, log P, and the solubility of ionizable drugs and small molecules using sub-milligram quantities of samples.

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

The SCISSOR is an in-vitro subcutaneous injection site simulator that provides biopharma scientists insights into the behavior of their sub-Q drug candidates.

From small-scale R&D to large-scale manufacturing, Pion homogenizers deliver exceptional fluid processing for particle size reduction (micronization,) cell disruption, and the creation of stable micro- and nanoemulsions and dispersions. Built for scalability, we make the transition from lab to commercial production seamless. Trusted by pharmaceutical, biotech, cannabis, chemical, and food and beverage manufacturers worldwide.

The PromoCell Macrophage Generation Media were developed for easy and efficient generation of the full spectrum of M1- and M2-polarized macrophages directly from freshly isolated peripheral blood monocytes.

PromoCell introduces the next generation 3D Tumorsphere Medium. This medium has been designed to meet your requirements for the extended serial culture of tumospheres. Our 3D Tumorsphere Medium supports the culture of the most commonly used cancer cell lines.

Xeno-free medium for the standardized in vitro cultivation of established cancer cell lines.

Serum- and BPE-free medium for an optimal and standardized differentiation of airway epithelial cells at air-liquid interface (ALI).

Fully automated and integrated platform to purify nucleic acids of the highest yield and purity for downstream applications.

MP Magnetic Rack 8 is a novel tool designed for fast and easy extraction of nucleic acids using a magnetic method. It is commonly used in combination with MagBeads FastDNA Kits from MP Biomedicals.  

MP Magnetic Rack 24 is a novel tool designed for fast and easy extraction of nucleic acids using a magnetic method.  

Albumin Bovine, Fraction V

FastGro is a fully define medium that allows culturing cells in vitro without the use of serum and without any animal or human derived compound.  

Formulated for isolation of mononuclear cells from defibrinated or heparinized whole human blood, as well as blood from other species.  

With the Beacon system’s light-speed workflows, you’ll gain insights, iterate and innovate. Replace a roomful of equipment with the Beacon system Work fast with individual cells  Perform assays at any time, as often as you need Track phenotype and genotype of single cells or clones Automate and scale workflows beyond manual, time-intensive analysis Generate great insights through deep profiling of each cell or clone

The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.