Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Cyto-Surf® B

Sphere Bio

Cyto-Surf® B is required to operate Cyto-Mine®. It provides the surfactant necessary to make stable biocompatible picodroplets and is fully optimized for Cyto-Mine®.

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Cyto-Cartridges®

Sphere Bio

Cyto-Cartridge® provides the core microfluidic functions used by Cyto-Mine® to implement picodroplet workflows. It is a single-use, fully disposable device to ensure zero cross-contamination between runs and maintain cell quality.

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Pico-Break™

Sphere Bio

Pico-Break™ is used to gently reduce the stability of picodroplets in order to release cellular or molecular contents into an aqueous medium for subsequent processing.

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96 VVP Volume Verified Pipetting Channel Pipetting Head

Dynamic Devices

The Lynx Series Liquid Handling Robot's new 96 VVP head with Volume Verified Pipetting (VVP) offers the first air based 96 head with verified individual volumes in each channel. VVP implements real-time liquid handling feedback through the use of in-line flow sensors that exactly measure the volume of liquid being aspirated/dispensed in the tip. The actual volumetric measurement accommodates for liquid viscosity and temperatu…

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Normal and Disease State Tissue

BioIVT

BioIVT’s extensive, highly characterized, normal and disease-state tissue samples are collected and prepared under strict ethical and QC policies and feature detailed clinical data as well as pathologist verification of disease tissue blocks to help ensure the accuracy of your research. Custom collections or extensive inventory are available from a diverse donor pool or any commercially available species.

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Target Sufficiency

Inotiv

Target Sufficiency® is the ability of a target system to respond to a therapeutic. It reflects the abundance and forms of the drug target protein, as well as other key system proteins that connect the target to disease phenotypes and enable response. Assessment of the target system requires an analysis platform that can simultaneously capture multiple precise protein measurements.

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ecTOF

Bruker Applied Mass Spectrometry

The ecTOF is the world’s first GC-HRMS with simultaneous acquisition of EI (Electron Ionization) and CI (Chemical Ionization) information in a single injection. While using EI as the gold-standard GC/MS ionization, the ecTOF in parallel operates a novel CI source. This way it simultaneously provides perfectly aligned accurate mass structural and molecular ion information within a single GC run.

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Preclinical Biomarker Services

Crown Bioscience

Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.

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PrepEngine

Pion, Inc

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

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