Drug discovery > Pre-Clinical Development Products & Reviews

The Total IGF-I immunoassay is a direct detection method which eliminates potential altering of sample matrix from size-exclusion chromatography or filtration methods.  

The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects.

During pregnancy, PAPP-A is produced in high concentrations by the trophoblast and released into maternal circulation. In addition to trophoblasts, PAPP-A expression has been reported in various tissues, including endometrium, testis, atherosclerotic arteries, kidney, bone, colon, and other adult and fetal tissue.

Activin B exhibits a wide range of biological activities, including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

Solutions for Life Science

Cutting edge brain research in awake mice without the biases introduced by anesthetics.

Tedlar® gas sampling bags are recommended in many US EPA methods including TCLP and methods TO-3 (VOCs), TO-12 (NMOC), TO-14A (VOCs), TO-15 (VOCs), ASTM D-5504 (reduced sulfur compounds) and a variety of atmospheric gas methods. Tedlar® bags are an excellent value and offer several features over competitor versions.   Benefits: Unique valve and seam-sealing process ensure bags are sturdy and leak-proof under the mo…

The ToxiLight® BioAssay Kit is a bioluminescent, non-destructive cytolysis assay kit designed to measure the release of the enzyme, adenylate kinase (AK), from damaged cells. The ToxiLight BioAssay Kit also facilitates high content screening by allowing other tests to be performed on the original cells For example, the ToxiLight BioAssay Kit is fully compatible with the ReportaLight™ BioAssay Kit, thus facilitating measurement…

Samplicity G2 Starter Bundle (Glossy Green) with 0.45 µm Millex-GP Filters

Fast, contamination free grinding below 1 micron. Handles sample volumes from 1 ml up to 4 x 225 ml.

In contrast to conventional Planetary Mills, the rotational speed of the grinding bowls and supporting disk can be configured separately in the Vario-Planetary Mill PULVERISETTE 4 classic line with 2 working stations. Your advantage: A single mill for mechanical activating and alloying providing optimum grinding conditions suited to the respective material to be ground and the size of the grinding bowls and balls! For resul…

Optimized for brewing yeast, wine yeast and other small cells with one channel of fluorescence.

AO/PI nuclear viability stain for primary cell samples

AO/PI nuclear viability stain for primary cell samples

AO nuclear stain to detect TNC

PI nuclear stain to detect dead nucleated cells

Cell permeable dye to detect metabolic activity in cells.

Cell viability and vitality kit to measure metabolic activity and dead/non-viable nucleated cells with Hoechst to determine total nucleated cell count.

DNA binding dye to stain live and dead cells

DNA binding dye to determine total nuclear cell count.

AO/PI nuclear viability stain for yeast cell samples

AO/PI nuclear viability stain for yeast cell samples

Buffer for use with yeast live/dead staining kit

Determine metabolic activity of Lager and Ale yeast.

Staining solution to detect apoptotic cells